4-(1H-Pyrazol-1-yl)benzene-1-sulfonylchloride - Names and Identifiers
4-(1H-Pyrazol-1-yl)benzene-1-sulfonylchloride - Physico-chemical Properties
Molecular Formula | C9H7ClN2O2S
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Molar Mass | 242.68 |
Density | 1.46g/cm3 |
Melting Point | 109℃ |
Boling Point | 360.2°C at 760 mmHg |
Flash Point | 171.7°C |
Vapor Presure | 4.68E-05mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.648 |
4-(1H-Pyrazol-1-yl)benzene-1-sulfonylchloride - Risk and Safety
Hazard Symbols | C - Corrosive
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Risk Codes | R34 - Causes burns
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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Hazard Note | Corrosive |
4-(1H-Pyrazol-1-yl)benzene-1-sulfonylchloride - Introduction
4-(1H-pyrazol-1-yl)benzenesulfonyl chloride, chemical formula C9H6ClNO2S, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
4-(1H-pyrazol-1-yl)benzenesulfonyl chloride is a white crystal with a strong pungent odor. It is poorly soluble in water and soluble in organic solvents such as ether and methylene chloride. It is a strong acidic compound with good reactivity.
Use:
4-(1H-pyrazol-1-yl)benzenesulfonyl chloride is widely used in organic synthesis. It can be used as an acylating agent for introducing a sulfonyl chloride group to form a compound having a specific functional group. It is also commonly used in the synthesis of organic compounds such as pesticides, pharmaceuticals and dyes.
Method:
4-(1H-pyrazol-1-yl)benzenesulfonyl chloride can be obtained by reacting 4-aminobenzenesulfonic acid with nitrosoyl. First, 4-aminobenzenesulfonic acid is reacted with nitrosyl to generate the corresponding pyrazole compound. Then, the pyrazole compound is reacted with sulfur chloride to obtain the target product 4-(1H-pyrazol-1-yl)benzenesulfonyl chloride.
Safety Information:
4-(1H-pyrazol-1-yl) benzensulfonyl chloride is irritating and can cause irritation of the respiratory tract, eyes, and skin. When in use, should take appropriate protective measures, such as wearing protective glasses, gloves and masks. At the same time, avoid inhaling its vapor or dust. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a cool, dry place, avoiding contact with oxidants and strong bases to avoid dangerous reactions.
Last Update:2024-04-09 21:11:58