4,7-Difluoroisatin - Names and Identifiers
Name | 4,7-Difluoroisatin
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Synonyms | 4,7-DIFLUOROISATIN 4,7-Difluoroisatin UKRORGSYN-BB BBV-037169 4,7-Difluoro indole-2,3-dione 4,7-DIFLUOROINDOLINE-2,3-DIONE 1H-Indole-2,3-dione, 4,7-difluoro- 4,7-Difluoro-2,3-dihydro-1H-indole-2,3-dione
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CAS | 749240-52-6
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4,7-Difluoroisatin - Physico-chemical Properties
Molecular Formula | C8H3F2NO2
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Molar Mass | 183.11 |
Density | 1.578±0.06 g/cm3(Predicted) |
pKa | 7.24±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
4,7-Difluoroisatin - Introduction
4,7-Difluoroisatin(4,7-Difluoroisatin) is an organic compound whose chemical formula is C8H3F2NO2. The following is a description of the nature, use, preparation and safety information of 4,7-Difluoroisatin:
Nature:
-Appearance: 4,7-Difluoroisatin is a pale yellow crystalline solid.
-Solubility: It is almost insoluble in water, slightly soluble in organic solvents such as ethanol, chloroform and ether.
-Melting point: Its melting point is about 220-230°C.
Use:
- 4,7-Difluoroisatin is widely used as an intermediate and catalyst in organic synthesis. It can be used to synthesize heterocyclic compounds and natural products.
-It can also be used as a dye and colorant, and is commonly used in industrial applications such as cosmetics, plastics, and printing inks.
Preparation Method:
-The preparation of 4,7-Difluoroisatin is generally carried out by using indigo acid (Isatin) as a raw material and synthesizing by introducing a fluorine atom in the reaction.
-The rough preparation steps include reacting indigo acid with a fluorinating agent (such as gaseous fluorine, cesium fluoride, etc.) to generate a derivative of 4,7-Difluoroisatin, which is then further processed to extract the pure product.
Safety Information:
- 4,7-Difluoroisatin has low toxicity, but it is still necessary to pay attention to follow laboratory safety regulations during operation.
-Avoid contact with skin and eyes. If contact occurs, rinse immediately with plenty of water.
-Keep away from fire and high temperature during storage and handling.
-Please seal the preservation, avoid contact with oxidants, strong acid or alkali and other substances.
Last Update:2024-04-09 02:00:48