4,6-dichloroisoindolin-1-one - Names and Identifiers
4,6-dichloroisoindolin-1-one - Physico-chemical Properties
Molecular Formula | C8H5Cl2NO
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Molar Mass | 202.04 |
Boling Point |
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Storage Condition | 2-8°C |
4,6-dichloroisoindolin-1-one - Introduction
4,6-dichloroisoindolin-1-one is an organic compound with the chemical formula C8H4Cl2NO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 4,6-dichloroisoindolin-1-one is a white solid.
-Solubility: It has good solubility in organic solvents, such as ethanol and dichloromethane. The solubility in water is low.
-Melting point: The melting point of 4,6-dichloroisoindolin-1-one is about 160-165 degrees Celsius.
Use:
- 4,6-dichloroisoindolin-1-one is an important intermediate in organic synthesis.
-It is widely used in the field of medicine as one of the raw materials for synthetic drugs.
-It can also be used for the synthesis of dyes and the preparation of battery materials.
Preparation Method:
4,6-dichloroisoindolin-1-one can be prepared by the following steps:
1. First, 2,4-dichloro -1H-indole and ethanone are reacted under alkaline conditions. The molecule formed during this reaction is a carboxylate.
2. Next, the carboxylate is oxidized to ketone under the action of an oxidizing agent.
Safety Information:
- 4,6-dichloroisoindolin-1-one has no obvious toxicity under normal use conditions.
-However, it is a chemical, and general laboratory safety practices should be followed, including wearing appropriate personal protective equipment, avoiding direct contact with skin and eyes, ensuring good ventilation, and avoiding inhalation of gases or dust.
-If ingested or inhaled, seek medical attention immediately.
Last Update:2024-04-09 21:01:54