393105-53-8
Tiplaxtinin
CAS: 393105-53-8
Molecular Formula: C24H16F3NO4
393105-53-8 - Names and Identifiers
393105-53-8 - Physico-chemical Properties
| Molecular Formula | C24H16F3NO4 |
| Molar Mass | 439.38 |
| Density | 1.34 |
| Melting Point | 164-167℃ |
| Solubility | DMSO (Sparingly), Methanol (Slightly) |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | -20°C |
| In vitro study | In a panel of human bladder cancer cell lines, PAI-1 reduced cell proliferation, cell adhesion, and colony formation, and induced apoptosis and anodyne apoptosis. |
| In vivo study | In a rat carotid artery thrombosis model, Tiplaxtinin (1 mg/kg, p.o.) increases the time to occlusion and prevents a decrease in carotid artery blood flow. In C57BL/6J mice, Tiplaxtinin(1 mg/g food) attenuated Ang II-induced aortic remodeling. Tiplaxtinin (p.o.) restores skeletal muscle regeneration in untreated type 1 diabetic mice. In athymic mice bearing human cancer cell lines T24 and HeLa xenografts, Tiplaxtinin (1 mg/kg, p. Et al. o.) decreased tumor xenograft growth is associated with decreased tumor angiogenesis, decreased cell proliferation, and increased apoptosis. |
393105-53-8 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.276 ml | 11.38 ml | 22.759 ml |
| 5 mM | 0.455 ml | 2.276 ml | 4.552 ml |
| 10 mM | 0.228 ml | 1.138 ml | 2.276 ml |
| 5 mM | 0.046 ml | 0.228 ml | 0.455 ml |
Last Update：2024-01-02 23:10:35
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Product Name: PAI-039; Tiplasinin Visit Supplier Webpage Request for quotationCAS: 393105-53-8
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Product Name: 2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic aci d Visit Supplier Webpage Request for quotationCAS: 393105-53-8
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View History
393105-53-8
4H-Naphtho[1,2-b]pyran-4-one,2-(4-methoxyphenyl)-
1-[(3,5-dimethyl-1,2-oxazole-4-)sulfonyl]-4-methoxypyrrolidine-2-carboxylic acid
1261966-75-9
N,N-diisopropylmethylphosphonamidic chloride
5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
362044-01-7
4H-Naphtho[1,2-b]pyran-4-one,2-(4-methoxyphenyl)-
1-[(3,5-dimethyl-1,2-oxazole-4-)sulfonyl]-4-methoxypyrrolidine-2-carboxylic acid
1261966-75-9
N,N-diisopropylmethylphosphonamidic chloride
5,6-Difluoro-1,2,3,4-tetrahydro-2-methylquinoline
362044-01-7