Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate is an organic compound with the chemical formula C10H8BrNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Use:
- Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate are commonly used as intermediates in organic synthesis.
-It can be used to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
The Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate is prepared as follows:
1. First prepare 6-bromoimidazo [1,2-A] pyridine-3-carboxylic acid:
-Reaction of pyridine and malonyldiazine in an anhydrous organic solvent to form its product.
-Bromination of the product to give 6-bromoimidazo [1,2-A] pyridine-3-carboxylic acid.
2. Preparation of Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate:
-6-Bromoimidazo [1,2-A] pyridine-3-carboxylic acid is reacted with acetic anhydride to produce an ethyl ester derivative.
Safety Information:
- Ethyl6-bromoimidazo[1,2-a]pyridine-3-carboxylate low toxicity, as a chemical substance, it should still be handled and stored safely.
-Avoid direct contact with skin and eyes, and ensure that good ventilation is provided during operation.
-Always wear appropriate protective equipment such as lab gloves and goggles when using the compound.
-If inhaled or ingested by mistake, seek medical attention immediately.