351534-36-6 - Names and Identifiers
351534-36-6 - Physico-chemical Properties
Molecular Formula | C11H14BrN
|
Molar Mass | 240.14 |
Density | 1.313g/cm3 |
Boling Point | 306.6°C at 760 mmHg |
Flash Point | 139.3°C |
Vapor Presure | 0.000762mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.553 |
351534-36-6 - Introduction
4-(3-Bromophenyl)piperidine is an organic compound with the chemical formula C11H14BrN. It has a solid form with the appearance of a white crystalline powder.
4-(3-Bromophenyl)piperidine is a drug intermediate, which is widely used in the field of drug synthesis. It can be used to synthesize a variety of drugs, such as antidepressants, antipsychotics and anticonvulsants. The nitrogen-containing heterocycles and substituents in its structure provide abundant reaction sites, which makes this compound have important application value in drug synthesis.
A method for preparing 4-(3-Bromophenyl)piperidine can be obtained by a reaction of piperidine and 3-bromoacetophenone. First, the amination reaction of piperidine with an amino group produces piperidine. The piperidine is then reacted with 3-bromoacetophenone in the presence of a chlorinating agent to produce 4-(3-Bromophenyl)piperidine. The reaction process requires steps such as thickening, temperature control, and an appropriate amount of washing and crystallization.
For safety information, 4-(3-Bromophenyl)piperidine should be considered toxic. During the operation, it is necessary to take necessary safety measures, such as wearing appropriate protective gloves, glasses, masks and protective clothing, and ensure that the operation is carried out in a well-ventilated laboratory. In addition, its storage and handling need to comply with relevant chemical safety regulations and avoid contact with oxidants, strong acids and strong bases. In the process of use and disposal, strictly abide by the environmental and occupational health and safety requirements. When using this compound, please refer to the relevant literature and expert guidance, and comply with relevant laws and regulations.
Last Update:2024-04-09 21:01:54