312272-59-6 - Names and Identifiers
Name | 5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine
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Synonyms | 5-(2-FLUOROPHENYL)-1,3,4-OXADIAZOL-2-AMINE 5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine 1,3,4-Oxadiazol-2-amine, 5-(2-fluorophenyl)- [5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]amine
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CAS | 312272-59-6
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312272-59-6 - Physico-chemical Properties
Molecular Formula | C8H6FN3O
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Molar Mass | 179.15 |
Density | 1.373±0.06 g/cm3(Predicted) |
Boling Point | 333.8±44.0 °C(Predicted) |
pKa | -1.62±0.13(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD00468338 |
312272-59-6 - Risk and Safety
312272-59-6 - Introduction
5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Usually a white or light yellow solid.
-Molecular formula: C8H6FN3O.
-Molecular weight: 183.15g/mol.
-Melting point: about 128-130 degrees Celsius.
-Solubility: Soluble in many organic solvents, such as dichloromethane, ethanol and dimethyl sulfoxide.
Use:
- 5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine has certain application potential in the agricultural field, and may be used as an insecticide to inhibit the growth and development of insects.
-It may also be used in medical research and the development of new drugs.
Preparation Method:
The preparation of -5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine generally involves a two-step reaction.
-First, through appropriate reaction conditions, 2-aminobenzoic acid is reacted with thionyl chloride to generate 2-aminobenzoyl sulfoxide.
-Then, in the presence of a strong base, 2-aminobenzoyl sulfoxide reacts with fluoroacetophenone to obtain the target product 5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine.
Safety Information:
- 5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-amine toxicity and danger has not been fully studied, so in the use and handling of the need to follow appropriate safety procedures.
-It should be kept away from fire and heat sources, stored in a sealed container, and avoid contact with oxidants and strong acids.
-Wear appropriate personal protective equipment such as goggles, gloves and laboratory clothing when used.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help. If swallowed, seek medical attention immediately.
Last Update:2024-04-09 21:01:54