(2,4, 6-triisopropyl) phenyl) Di-cyclohexylphosphine is an organophosphorus compound with the chemical formula C38H57P. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
-Appearance: Colorless to light yellow crystalline
-Solubility: Soluble in organic solvents such as ether and chloroform
-Melting point: About 90-94 ° C
-Boiling point: About 300 ° C
-Density: approx. 0.93g/cm³
Use:
-As a ligand: the phosphorus ligand in the double throat compound can be used in organometallic catalyzed reactions, such as cross-coupling reactions and hydrogenation reactions.
-Catalyst: It can be used as platinum catalyst and phosphine ligand for certain metal catalyzed reactions.
-Organic synthesis: It can be used to synthesize some intermediates in drugs and pesticides.
Method:
The preparation of (2,4, 6-triisopropyl) phenyl) Di-cyclohexylphosphine is usually carried out by the following steps:
1. Starting with (2,4, 6-triisopropyl) phenyl methyl ketone
2. The starting material reacts with ethyl magnesium solution to generate the corresponding Grignard reagent
3. Grignard reagent reacts with phosphorus trichloride to generate (2,4, 6-triisopropyl) phenyl) Di-cyclohexyl phosphine
Safety Information:
-Use and store the compound to avoid contact with skin and eyes, and wear appropriate personal protective equipment.
-May have irritating effects and cause irritation to the respiratory system and skin.
-Avoid contact with oxygen and moisture during storage to prevent dangerous reactions.
-Detailed safety information should refer to the safety data sheet of the compound.