3-氨基-6-氯-2-吡啶羧酰胺
6-Chloro-3-aminopyridine-2-carboxamide
CAS: 175358-01-7
Molecular Formula: C6H6ClN3O
3-氨基-6-氯-2-吡啶羧酰胺 - Names and Identifiers
| Name | 6-Chloro-3-aminopyridine-2-carboxamide |
| Synonyms | 3-amino-6-chloropicolinamide [3-AMINO-6-CHLOROPICOLIMIDE] 3-aMino-6-chloropyridine-2-carboxaMide 6-Chloro-3-aminopyridine-2-carboxamide 3-amino-6-chloropyridine-2-carboxamide 2-Pyridinecarboxamide, 3-amino-6-chloro- 3-AMino-6-chloro-pyridine-2-carboxylic acid aMide |
| CAS | 175358-01-7 |
| EINECS | 829-520-3 |
| InChI | InChI=1/C6H6ClN3O/c7-4-2-1-3(8)5(10-4)6(9)11/h1-2H,8H2,(H2,9,11) |
3-氨基-6-氯-2-吡啶羧酰胺 - Physico-chemical Properties
| Molecular Formula | C6H6ClN3O |
| Molar Mass | 171.58 |
| Density | 1.484±0.06 g/cm3(Predicted) |
| Boling Point | 349.3±42.0 °C(Predicted) |
| Flash Point | 165.053°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 14.26±0.50(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.655 |
3-氨基-6-氯-2-吡啶羧酰胺 - Introduction
The chemical formula C7H7ClN2O is an organic compound.
Nature:
It is a solid with a white to light yellow appearance. It is soluble in water and in organic solvents such as alcohols and ethers.
Use:
It is often used in the synthesis of organic compounds such as pesticides, pharmaceuticals and dyes. It is an important intermediate that can be used in the synthesis of various organic compounds.
Method:
A common preparation method is to react 3-aminopyridine with 6-chloropyridine-2-carboxylic acid. First, 3-aminopyridine is dissolved in an acidic solution, then thionyl chloride or phosphorus chloride is added as a catalyst, and finally 6-chloropyridine-2-carboxylic acid is added for reaction. After completion of the reaction, the target product is obtained by a method such as crystallization or extraction.
Safety Information:
It is relatively stable under general conditions, but contact with strong oxidants should be avoided. During operation, it is necessary to wear appropriate protective measures, such as laboratory gloves, protective glasses and laboratory coats, to prevent skin and eye contact. Proper laboratory practices and safe operating procedures should be followed during use or storage. In case of misuse, inhalation or skin contact, seek medical attention immediately.
Nature:
It is a solid with a white to light yellow appearance. It is soluble in water and in organic solvents such as alcohols and ethers.
Use:
It is often used in the synthesis of organic compounds such as pesticides, pharmaceuticals and dyes. It is an important intermediate that can be used in the synthesis of various organic compounds.
Method:
A common preparation method is to react 3-aminopyridine with 6-chloropyridine-2-carboxylic acid. First, 3-aminopyridine is dissolved in an acidic solution, then thionyl chloride or phosphorus chloride is added as a catalyst, and finally 6-chloropyridine-2-carboxylic acid is added for reaction. After completion of the reaction, the target product is obtained by a method such as crystallization or extraction.
Safety Information:
It is relatively stable under general conditions, but contact with strong oxidants should be avoided. During operation, it is necessary to wear appropriate protective measures, such as laboratory gloves, protective glasses and laboratory coats, to prevent skin and eye contact. Proper laboratory practices and safe operating procedures should be followed during use or storage. In case of misuse, inhalation or skin contact, seek medical attention immediately.
Last Update：2024-04-09 21:01:54
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View History
3-氨基-6-氯-2-吡啶羧酰胺
BENZOIC ACID, 5-BROMO-2-[[[(PHENOXYACETYL)AMINO]THIOXOMETHYL]AMINO]-
2S-氨基-3R-硬脂醇
3-溴-2-甲酰基吡啶
庚基-Β-D-吡喃葡萄糖苷
4-正十二烷氧基苯甲酸
P-NITRO BLUE TETRAZONIUM CHLORIDE
((4-环丙基-5-巯基-4H-1,2,4-三唑-3-基)甲基)氨基甲酸叔丁酯
ETHYL 5'-BENZAMIDO-2'-(PIPERIDIN-1-YLMETHYL)-2,3'-BITHIOPHENE-4'-CARBOXYLATE
SPDP-PEG6-NHS ester
BENZOIC ACID, 5-BROMO-2-[[[(PHENOXYACETYL)AMINO]THIOXOMETHYL]AMINO]-
2S-氨基-3R-硬脂醇
3-溴-2-甲酰基吡啶
庚基-Β-D-吡喃葡萄糖苷
4-正十二烷氧基苯甲酸
P-NITRO BLUE TETRAZONIUM CHLORIDE
((4-环丙基-5-巯基-4H-1,2,4-三唑-3-基)甲基)氨基甲酸叔丁酯
ETHYL 5'-BENZAMIDO-2'-(PIPERIDIN-1-YLMETHYL)-2,3'-BITHIOPHENE-4'-CARBOXYLATE
SPDP-PEG6-NHS ester