3-叠氮基-2,3-二脱氧-1-O-(叔丁基二甲基甲硅烷基)-Β-D-己吡喃阿拉伯糖 - Names and Identifiers
Name | 3-azido-2,3-dideoxy-1-O-(T-butyldimethyl-silyl)-B
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Synonyms | 3-azido-2,3-dideoxy-1-O-(T-butyldimethyl-silyl)-B 3-Azido-2,3-dideoxy-1-O-(tert-butyldimethylsilyl)-b-D-arabino-hexopyranose 3-azido-2,3-dideoxy-1-o-(tert-butyldimethylsilyl)-β-d-arabino-hexopyranose 3-AZIDO-2,3-DIDEOXY-1-O-(T-BUTYLDIMETHYL -SILYL)-BETA-D-ARABINO-HEXOPYRANOSE
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CAS | 189454-43-1
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InChI | InChI=1/C12H25N3O4Si/c1-12(2,3)20(4,5)19-10-6-8(14-15-13)11(17)9(7-16)18-10/h8-11,16-17H,6-7H2,1-5H3/t8-,9-,10+,11+/m1/s1 |
3-叠氮基-2,3-二脱氧-1-O-(叔丁基二甲基甲硅烷基)-Β-D-己吡喃阿拉伯糖 - Physico-chemical Properties
Molecular Formula | C12H25N3O4Si
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Molar Mass | 303.43 |
Melting Point | 73-75°C(lit.) |
Storage Condition | Room Temprature |
3-叠氮基-2,3-二脱氧-1-O-(叔丁基二甲基甲硅烷基)-Β-D-己吡喃阿拉伯糖 - Risk and Safety
WGK Germany | 3 |
HS Code | 29329990 |
3-叠氮基-2,3-二脱氧-1-O-(叔丁基二甲基甲硅烷基)-Β-D-己吡喃阿拉伯糖 - Introduction
3-azido-2,3-dideoxy-1-O-(T-butyldimethyl-silyl)-B is an organic compound with the chemical formula C16H30N4O6Si.
This compound has the following properties:
-Appearance: Polycrystalline solid, white or yellow powder.
-Solubility: Soluble in water, methanol and ethanol.
-Melting point: About 185-190 ℃.
3-azido-2,3-dideoxy-1-O-(T-butyldimethyl-silyl)-B uses mainly include:
-Chemical synthesis: It can be used as an intermediate in organic synthesis and used in the synthesis of other compounds.
-Pharmaceutical research: May be used for anti-tumor, anti-viral and anti-bacterial drug research.
The method for preparing 3-azido-2,3-dideoxy-1-O-(T-butyldimethyl-silyl)-B is generally as follows:
First, D-arabino-hexampyranose is sulfated with sulfuric acid to obtain 6-O-sulfate-β-D-arabino-hexampyranose. Then, the sulfate group is converted to N-methyl-N-azidothioamide by chemical reaction, and the final product is obtained by reduction, protection and siliconization.
Regarding safety information, 3-azido-2,3-dideoxy-1-O-(T-butyldimethyl-silyl)-B is a chemical reagent used in industrial environments such as laboratories, and the following precautions should be observed:
-Wear personal protective equipment during operation, including safety glasses, gloves, protective clothing, etc.
-Avoid inhalation, ingestion or contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical attention.
-should be in a well-ventilated place to operate, avoid inhalation of its steam.
-Avoid contact with harmful substances such as oxidants, acids and alkalis during storage.
-The substance and its packaging must be disposed of correctly in accordance with the relevant legislation.
Please note that due to the toxicity and chemical activity of this compound, it must be handled and stored by professionals under suitable laboratory conditions and follow relevant safe operating procedures.
Last Update:2024-04-09 21:01:54