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3-三氟甲氧基溴苄

3-(Trifluoromethoxy)benzyl bromide

CAS: 159689-88-0

Molecular Formula: C8H6BrF3O

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3-三氟甲氧基溴苄 - Names and Identifiers

Name 3-(Trifluoromethoxy)benzyl bromide
Synonyms 2-fluoropyridin-3-amine
3-(Trifluoromethoxy)benzyl bromide
3-(TRIFLUOROMETHOXY)BENZYL BROMIDE
à-bromo-3-(trifluoromethoxy)toluene
a-Bromo-3-(trifluoromethoxy)toluene
1-(chloromethyl)-3,5-dimethoxybenzene
alpha-Bromo-3-(trifluoromethoxy)toluene
1-(Bromomethyl)-3-(trifluoromethoxy)benzene
1-(BROMOMETHYL)-3-(TRIFLUOROMETHOXY)BENZENE
1-(Bromomethyl)-3-(trifluoromethoxy)benzene, alpha-Bromo-3-(trifluoromethoxy)toluene
CAS 159689-88-0
InChI InChI=1/C8H4BrF3O2/c9-7(13)5-2-1-3-6(4-5)14-8(10,11)12/h1-4H/p+1

3-三氟甲氧基溴苄 - Physico-chemical Properties

Molecular FormulaC8H6BrF3O
Molar Mass255.03
Density1.572g/mLat 25°C(lit.)
Boling Point179°C(lit.)
Flash Point192°F
Specific Gravity1.5838
BRN8052203
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
SensitiveLachrymatory
Refractive Indexn20/D 1.478(lit.)

3-三氟甲氧基溴苄 - Risk and Safety

Hazard SymbolsC - Corrosive
Corrosive
Risk Codes34 - Causes burns
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 - Take off immediately all contaminated clothing.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 3265 8/PG 2
WGK Germany3
HS Code29093090
Hazard NoteCorrosive/Lachrymatory
Hazard Class8
Packing GroupIII

3-三氟甲氧基溴苄 - Introduction

3-(Trifluoromethoxy)benzyl bromide is an organic compound with the chemical formula C9H8BrF3O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to light yellow liquid.
-Density: 1.624 g/mL.
-Boiling point: 173-175 ° C.
-Melting point:-15 ° C.
-Solubility: Soluble in most organic solvents, such as ethanol, dimethylformamide and a small amount of water.

Use:
- 3-(Trifluoromethoxy)benzyl bromide can be used as an important intermediate in organic synthesis. It can be used to synthesize biologically active compounds, such as anti-tumor drugs, anti-viral drugs, etc.
-It can also be used as a synthesis catalyst and a stabilizer for polymers.

Method:
3-(Trifluoromethoxy)benzyl bromide can be prepared by the following steps:
1. Add trifluoromethanol to the benzyl bromide reactant.
2. A base catalyst such as sodium hydride or Potassium hydride is added to the reaction solution.
3. Stir and heat the reaction mixture at an appropriate temperature.
4. Subsequently, the target product is extracted and purified from the reaction mixture through steps such as extraction and washing.

Safety Information:
- 3-(Trifluoromethoxy)benzyl bromide needs to be careful to prevent contact with skin and eyes during operation and storage.
-Good ventilation and personal protective measures such as gloves, goggles and protective clothing should be taken when handling the compound.
-When using or disposing of the compound, it is necessary to follow local safety practices and regulatory requirements.
-When disposing of the waste of this compound, it should be properly disposed of and comply with relevant regulatory requirements.
Last Update:2024-04-09 19:05:47
3-三氟甲氧基溴苄
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SKYRUN INDUSTRIAL CO.,LTD
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Product Name: 3-(TRIFLUOROMETHOXY)BENZYL BROMIDE Visit Supplier Webpage Request for quotation
CAS: 159689-88-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
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QQ: 2531159185 Click to send a QQ messageSend QQ message
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 3-(Trifluoromethoxy)benzyl Bromide Visit Supplier Webpage Request for quotation
CAS: 159689-88-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: 3-(Trifluoromethoxy)benzyl Bromide Visit Supplier Webpage Request for quotation
CAS: 159689-88-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
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