3-nitro-6-phenyl-1H-pyridin-2-one - Names and Identifiers
3-nitro-6-phenyl-1H-pyridin-2-one - Physico-chemical Properties
3-nitro-6-phenyl-1H-pyridin-2-one - Introduction
2(1H)-Pyridinone, 3-nitro-6-phenyl-is an organic compound with the chemical formula C11H8N2O3. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to yellow crystalline powder
-Melting point: 187-189°C
-Boiling point: 452.7°C
-Density: 1.42g/cm³
-Solubility: slightly soluble in water, soluble in alcohol, ether, ketone and other organic solvents
-Stability: stable, but avoid contact with strong oxidants
Use:
- 2(1H)-Pyridinone, 3-nitro-6-phenyl-is an important organic synthesis intermediate that can be used to synthesize various organic compounds.
-It is often used to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
2(1H)-Pyridinone, 3-nitro-6-phenyl-can be obtained by condensation reaction of benzoic acid and 2-hydroxy-6-nitropyridine. Specific steps are as follows:
1. Mix benzoic acid and 2-hydroxy-6-nitropyridine in a molar ratio of 1:1.
2. Add an appropriate amount of solvent, such as methanol or ethanol, to the reaction vessel.
3. slowly raise the temperature to the reaction temperature, and react for a period of time.
4. After completion of the reaction, the reactant is filtered, washed and dried to obtain the target product.
Safety Information:
- 2(1H)-Pyridinone, 3-nitro-6-phenyl-has low toxicity, but it is still necessary to pay attention to safe operation.
-use should wear protective glasses and gloves, avoid contact with skin and eyes.
-A well-ventilated laboratory environment should be maintained during operation.
-Need to be stored in a closed container, away from fire and oxidizing agents.
-In the disposal of waste, should follow the local regulations, do not dump.
Last Update:2024-04-09 02:00:45