{3-[(2-methylacryloyl)amino]phenyl}boronic acid is an organic compound whose molecular formula is C11H13BNO3.
Nature:
-Appearance as a white crystalline solid.
-Soluble in organic solvents such as dimethylformamide and dichloromethane.
-Low solubility in water.
-Air wet oxidation reaction may occur, so it should be stored in a dry, inert gas environment.
Use:
{3-[(2-methylacryloyl)amino]phenyl}boronic acid is an organic boron ligand that can be used in organic synthesis reactions, such:
-As a ligand of metal catalyst, it participates in Suzuki reaction and Heck reaction.
-As an intermediate in the synthesis of drugs.
-can be used for the synthesis of fluorescent dyes and fluorescent probes.
Preparation Method:
{3-[(2-methylacryloyl)amino]phenyl}boronic acid has many preparation methods. A common method is:
2-aminophenylboronic acid and methacrylamide are reacted by heating in an appropriate solvent, and then purified by crystallization to obtain the target product.
Safety Information:
- {3-[(2-methylacryloyl)amino]phenyl}boronic acid shall be operated in accordance with the safety operation specifications of general organic chemical synthesis.
-May cause irritation to eyes, skin and respiratory system, avoid contact.
-Use personal protective equipment such as gloves and goggles when handling.
-Store away from fire and oxidant, and keep sealed and dry.