3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide

3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide - Names and Identifiers

Name	N-(3-Hydroxytetradecanoyl)-DL-hoMoserine lactone
Synonyms	N-(3-oxodecanoyl)-homoserine lactone 3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide N-(3-Hydroxytetradecanoyl)-DL-hoMoserine lactone 3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide Tetradecanamide, 3-hydroxy-N-(tetrahydro-2-oxo-3-furanyl)-
CAS	172670-99-4

3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide - Physico-chemical Properties

Molecular Formula	C18H33NO4
Molar Mass	327.46
Density	1.04±0.1 g/cm3(Predicted)
Boling Point	549.3±50.0 °C(Predicted)
pKa	14.23±0.20(Predicted)
Storage Condition	-20°C
In vitro study	Moderate levels of exogenous N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone; 10 and 20 μM) can induce or enhance biofilm formation and alter its structure, while high levels (40 and 100 μM) does not significantly improve and even inhibits biofilm formation in V. alginolyticus . N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (2, 5, 10, 20 μM; 36 hours) increases the biofilms of strain N°24 significantly. Moderate addition of N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone (10 or 20 μM) also increases biofilm formation of non-AHL-producing peanut-nodulating bacteria.

3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2811 6.1 / PGIII
WGK Germany	3

3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide - References

biological activity

N-(3-hydroxytradecanoyl)-DL-homoserine lactone (N-(3-oxodecanoyl)-homoserine lactone) is a member of N-acyl homoserine lactones (AHL) from Vibrio alginolyticus strains. N-(3-hydroxytetraecanoyl)-DL-homoserine lactone is used for biofilm formation and has antibacterial activity.

Last Update：2024-04-09 15:16:59

3-hydroxy-N-(2-oxooxolan-3-yl)tetradecanamide

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