3-amino-5-chloro-2-indolinone
3-Amino-5-chloro-1,3-dihydro-2H-indol-2-onehydrochloride
CAS: 1104895-64-8
Molecular Formula: C8H7ClN2O
3-amino-5-chloro-2-indolinone - Names and Identifiers
3-amino-5-chloro-2-indolinone - Physico-chemical Properties
| Molecular Formula | C8H7ClN2O |
| Molar Mass | 182.61 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12197342 |
3-amino-5-chloro-2-indolinone - Introduction
3-Amino-5-loro-1, (3-amino-5-chloro-1, 3-dihydro-2H-indol-2-one hydrochloride), also known as arsine hydrochloride, is an organic compound.
Nature:
-Appearance: White crystalline solid
-Melting point: about 212-216°C
-Soluble in water and some organic solvents
Use:
-3-Amino-5-chroo-1 is used as an intermediate in pharmaceutical chemistry to synthesize some drug molecules.
-It can also be used as a catalyst in organic synthesis reactions.
Preparation Method:
3-Amino-5-chroo-1, can be synthesized by the following steps:
1. Starting from 3-nitro-4-chrooaniline, it is reduced to 3-amino-4-chrooaniline by hydrogenation reduction.
2. 3-amino-4-choroaniline and acetone undergo a condensation reaction under acidic conditions to produce 3-amino-5-choro-1, 3-dihydro-2H-indol-2-one.
3. Finally, 3-amino-5-chloro-1,3-dihydro-2H-indol-2-one was reacted with hydrochloric acid to give 3-Amino-5-chloro-1.
Safety Information:
- 3-Amino-5-chloro-1, which is a chemical used and should follow safe operating procedures.
-It may be irritating to the eyes, skin and respiratory tract. Wear appropriate protective measures when using it.
-Avoid inhaling its dust or solution, and avoid contact with skin and eyes.
-Maintain good ventilation during use.
-During storage and handling, avoid contact with oxidants, strong acids, strong bases and other substances.
Nature:
-Appearance: White crystalline solid
-Melting point: about 212-216°C
-Soluble in water and some organic solvents
Use:
-3-Amino-5-chroo-1 is used as an intermediate in pharmaceutical chemistry to synthesize some drug molecules.
-It can also be used as a catalyst in organic synthesis reactions.
Preparation Method:
3-Amino-5-chroo-1, can be synthesized by the following steps:
1. Starting from 3-nitro-4-chrooaniline, it is reduced to 3-amino-4-chrooaniline by hydrogenation reduction.
2. 3-amino-4-choroaniline and acetone undergo a condensation reaction under acidic conditions to produce 3-amino-5-choro-1, 3-dihydro-2H-indol-2-one.
3. Finally, 3-amino-5-chloro-1,3-dihydro-2H-indol-2-one was reacted with hydrochloric acid to give 3-Amino-5-chloro-1.
Safety Information:
- 3-Amino-5-chloro-1, which is a chemical used and should follow safe operating procedures.
-It may be irritating to the eyes, skin and respiratory tract. Wear appropriate protective measures when using it.
-Avoid inhaling its dust or solution, and avoid contact with skin and eyes.
-Maintain good ventilation during use.
-During storage and handling, avoid contact with oxidants, strong acids, strong bases and other substances.
Last Update：2024-04-09 21:00:56
