3-Trifluoromethyltrifluoroacetophenone - Names and Identifiers
Name | 3-trifluoromethyl-A,A,A-trifluoroacetophenone
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Synonyms | 3-Trifluoromethyltrifluoroacetophenone 3-TRIFLUOROMETHYL-A,A,A-TRIFLUOROACETOPHENONE 3-trifluoromethyl-A,A,A-trifluoroacetophenone 2,2,2-Trifluoro-3-(trifluoromethyl)-acetophenone 2,2,2-TRIFLUORO-3'-(TRIFLUOROMETHYL)ACETOPHENONE 2,2,2-TRIFLUORO-1-(3-TRIFLUOROMETHYLPHENYL)ETHANONE 2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]ethanone 3-Trifluoromethyl-alpha,alpha,alpha-trifluoroacetophenone ALPHA,ALPHA,ALPHA-TRIFLUORO-3-(TRIFLUOROMETHYL)ACETOPHENONE
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CAS | 721-37-9
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InChI | InChI=1/C9H4F6O/c10-8(11,12)6-3-1-2-5(4-6)7(16)9(13,14)15/h1-4H |
3-Trifluoromethyltrifluoroacetophenone - Physico-chemical Properties
Molecular Formula | C9H4F6O
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Molar Mass | 242.12 |
Density | 1.418g/mLat 25°C(lit.) |
Melting Point | 76-77 °C |
Boling Point | 65-67°C24mm Hg(lit.) |
Flash Point | 139°F |
Vapor Presure | 2.37mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | n20/D 1.415(lit.) |
3-Trifluoromethyltrifluoroacetophenone - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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UN IDs | UN 1224 3/PG 3 |
WGK Germany | 3 |
Hazard Note | Irritant/Lachrymator |
Hazard Class | 3.2 |
Packing Group | III |
3-Trifluoromethyltrifluoroacetophenone - Introduction
3-trifluoromethyl-A,A,A-trifluoroacetophenone, also known as 3-trifluoromethyl-α, α,α-trifluoroacetophenone, is an organic compound with the chemical formula C9H4F6O. The following is a description of the nature, use, preparation and safety information of this substance:
Nature:
-Appearance: Colorless to light yellow crystal
-Solubility: Soluble in organic solvents such as ethanol, methanol and dimethylformamide, slightly soluble in water
-Melting Point: 27-29°C
-Boiling Point: 135-137°C
-relative density: 1.61g/cm³
Use:
- 3-trifluoromethyl-A,A,A-trifluoroacetophenone can be used as an important intermediate in organic synthesis.
-It can be used to synthesize various compounds containing trifluoromethyl functional groups, such as pesticides, drugs and polymer materials.
-It can also be used as a ligand for metal organic catalysts.
Preparation Method:
3-trifluoromethyl-A,A,A-trifluoroacetophenone are usually prepared by a trifluoromethylation reaction. One of the commonly used methods is the reaction of dichlorotrifluoromethane and acetophenone under basic conditions to obtain the product.
Safety Information:
-3-trifluoromethy-A, A,A-trifluoroacetophenone generally has low toxicity under normal use conditions, but protective measures still need to be paid attention.
-Avoid skin contact and inhalation of vapors of this compound.
-When in use, should be equipped with appropriate protective equipment, such as protective gloves, glasses and respiratory protection.
-During storage and handling, care should be taken to avoid contact with oxidants and to prevent fire and explosion.
Generally speaking, 3-trifluoromethyl-A,A,A-trifluoroacetophenone is an important chemical intermediate, which can be used in organic synthesis and metal organic catalytic reactions, but it should be handled with caution and take corresponding safety precautions.
Last Update:2024-04-09 21:32:43