3-R-1-叔丁氧羰基哌啶甲酸
(R)-N-Boc-piperidine-3-carboxylic acid
CAS: 163438-09-3
Molecular Formula: C11H19NO4
3-R-1-叔丁氧羰基哌啶甲酸 - Names and Identifiers
3-R-1-叔丁氧羰基哌啶甲酸 - Physico-chemical Properties
| Molecular Formula | C11H19NO4 |
| Molar Mass | 229.27 |
| Density | 1.164±0.06 g/cm3(Predicted) |
| Boling Point | 353.2±35.0 °C(Predicted) |
| Flash Point | 167.4°C |
| Vapor Presure | 6.15E-06mmHg at 25°C |
| Appearance | White solid |
| Color | White |
| BRN | 5539297 |
| pKa | 4.49±0.20(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| MDL | MFCD02179173 |
3-R-1-叔丁氧羰基哌啶甲酸 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
3-R-1-叔丁氧羰基哌啶甲酸 - Introduction
(R)-N-Boc-piperidine-3-carboxylic acid is an organic compound with the following properties:
1. Appearance and physical properties:(R)-N-Boc-piperidine-3-carboxylic acid is a solid compound, usually white to white-like crystalline powder.
2. Chemical properties:(R)-N-Boc-piperidine-3-carboxylic acid is an ester compound, mainly composed of piperidine ring, formate group and Boc protecting group. It is a chiral compound with one optically active carbon atom. It can remove the Boc protecting group by acid or base catalyzed hydrolysis.
3. Application:(R)-N-Boc-piperidine-3-carboxylic acid is often used as a synthetic intermediate for chiral molecules in organic synthesis. It can be used as a precursor of chiral ligands and catalysts to participate in asymmetric catalytic reactions. It can also be used to synthesize other chiral compounds.
4. Preparation method:(R)-N-Boc-piperidine-3-carboxylic acid is generally prepared by a chemical synthesis method, and the specific process is as follows: first, 3-formylpiperidine is reacted with Boc2O to obtain (R)-N-Boc-piperidine-3-carboxylic acid.
5. Safety information: Regarding the safety of (R)-N-Boc-piperidine-3-carboxylic acid, the following points need to be paid attention to: During handling, you should wear appropriate personal protective equipment to avoid direct contact with skin and eyes. Operate in a well-ventilated area to avoid inhaling powders or vapors. When contact or accidental inhalation occurs, the affected area should be washed immediately and the advice of a doctor should be consulted. In addition, the compound should be stored and handled properly to avoid ignition or high temperatures. The specific safety operation information can be obtained from the safety data sheet.
1. Appearance and physical properties:(R)-N-Boc-piperidine-3-carboxylic acid is a solid compound, usually white to white-like crystalline powder.
2. Chemical properties:(R)-N-Boc-piperidine-3-carboxylic acid is an ester compound, mainly composed of piperidine ring, formate group and Boc protecting group. It is a chiral compound with one optically active carbon atom. It can remove the Boc protecting group by acid or base catalyzed hydrolysis.
3. Application:(R)-N-Boc-piperidine-3-carboxylic acid is often used as a synthetic intermediate for chiral molecules in organic synthesis. It can be used as a precursor of chiral ligands and catalysts to participate in asymmetric catalytic reactions. It can also be used to synthesize other chiral compounds.
4. Preparation method:(R)-N-Boc-piperidine-3-carboxylic acid is generally prepared by a chemical synthesis method, and the specific process is as follows: first, 3-formylpiperidine is reacted with Boc2O to obtain (R)-N-Boc-piperidine-3-carboxylic acid.
5. Safety information: Regarding the safety of (R)-N-Boc-piperidine-3-carboxylic acid, the following points need to be paid attention to: During handling, you should wear appropriate personal protective equipment to avoid direct contact with skin and eyes. Operate in a well-ventilated area to avoid inhaling powders or vapors. When contact or accidental inhalation occurs, the affected area should be washed immediately and the advice of a doctor should be consulted. In addition, the compound should be stored and handled properly to avoid ignition or high temperatures. The specific safety operation information can be obtained from the safety data sheet.
Last Update：2024-04-09 20:52:54
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View History
3-R-1-叔丁氧羰基哌啶甲酸
A-ETHYL-A-METHYL SUCCINIC ACID
4-Oxa-tricyclo[5.2.1.02,6]dec-8-en-3-one
盐酸环喷托酯 标准品
3-(吡啶-2-基)丙-2-炔-1-醇
[ANTHRACENE-9,10-DIYLBIS(METHYLENE)]BISPHOSPHONIC ACID TETRAETHYL ESTER
乙腈中醋酸曲安奈德标准溶液 100μg/mL
Isopentyl (2E)-3-phenyl-2-propenoate
A-ETHYL-A-METHYL SUCCINIC ACID
4-Oxa-tricyclo[5.2.1.02,6]dec-8-en-3-one
盐酸环喷托酯 标准品
3-(吡啶-2-基)丙-2-炔-1-醇
[ANTHRACENE-9,10-DIYLBIS(METHYLENE)]BISPHOSPHONIC ACID TETRAETHYL ESTER
乙腈中醋酸曲安奈德标准溶液 100μg/mL
Isopentyl (2E)-3-phenyl-2-propenoate