3-N-BOC-氨基-3-(4-CBZ)哌啶-丙酸 - Names and Identifiers
Name | 3-(1-benzyloxycarbonyl-4-piperidyl)-3-(tert-butoxycarbonylamino)propanoic acid
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Synonyms | 3-N-Boc-amino-3-(4'-Cbz)piperidi 4-(1-tert-Butoxycarbonylamino-2- 3-N-Boc-amino-3-(4'-Cbz)piperidine-propionic acid 3-(1-benzyloxycarbonyl-4-piperidyl)-3-(tert-butoxycarbonylamino)propanoic acid 3-(1-((Benzyloxy)carbonyl)piperidin-4-yl)-3-((tert-butoxycarbonyl)amino)propanoic acid beta-[[(tert-Butoxyl)carbonyl]amino]-1-[(phenylmethoxy)carbonyl]-4-piperidinepropanoic acid 4-Piperidinepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[(phenylmethoxy)carbonyl]- 4-Piperidinepropanoic acid, .beta.-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[(phenylmethoxy)carbonyl]-
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CAS | 886362-33-0
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InChI | InChI=1/C21H30N2O6/c1-21(2,3)29-19(26)22-17(13-18(24)25)16-9-11-23(12-10-16)20(27)28-14-15-7-5-4-6-8-15/h4-8,16-17H,9-14H2,1-3H3,(H,22,26)(H,24,25) |
3-N-BOC-氨基-3-(4-CBZ)哌啶-丙酸 - Physico-chemical Properties
Molecular Formula | C21H30N2O6
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Molar Mass | 406.47 |
Density | 1.204 |
Boling Point | 581.9±35.0 °C(Predicted) |
Flash Point | 305.7°C |
Vapor Presure | 2.22E-14mmHg at 25°C |
pKa | 4.40±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.54 |
3-N-BOC-氨基-3-(4-CBZ)哌啶-丙酸 - Introduction
3-(+)-3-(tert-butoxycarbonylamino)propanoic acid is an organic compound with the chemical formula C22H29N3O5. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Powder, soluble in organic solvents such as dimethylformamide (DMF), dichloromethane, etc.
-Molecular weight: 403.49g/mol.
-Melting point: about 114-116°C.
-Stable at room temperature.
Use:
3-(br)-3-(tert-butoxycarbonylamino)propanoic acid is commonly used as a reagent in organic synthesis. It can be used to prepare multifunctional compounds, such as peptides, catalysts, drugs and intermediates in organic synthesis.
Preparation Method:
3-(br)-3-(tert-butoxycarbonylamino)propanoic acid is usually prepared by chemical synthesis. The following is a common synthetic route:
1. First, by synthesizing 3-amino -3-(4 '-Cbz-piperidinyl) propionic acid (piperidinyl and Cbz groups are introduced through organic synthesis reactions).
2. Then, under appropriate conditions, the above compound is reacted with tert-butoxycarbonyisopropyl (tert-Boc) chloride to obtain 3-(r)-3-(tert-butoxycarbonylamino)propanoic acid.
Safety Information:
- 3-()-3-(tert-butoxycarbonylamino)propanoic acid in the laboratory operation should follow the chemical safety procedures.
-in contact to pay attention to protective measures, avoid inhalation, intake and contact with the skin.
-When storing, keep it in a dry, cool place, away from fire and oxidizing agents.
-Observe local codes and regulations when handling and disposing of this compound.
Last Update:2024-04-09 21:01:54