3-Ethyl-5-benzylidene-2-thioxothiazolidin-4-one
5-Benzylidene-3-ethyl rhodanine
CAS: 18331-34-5
Molecular Formula: C12H11NOS2
3-Ethyl-5-benzylidene-2-thioxothiazolidin-4-one - Names and Identifiers
3-Ethyl-5-benzylidene-2-thioxothiazolidin-4-one - Physico-chemical Properties
| Molecular Formula | C12H11NOS2 |
| Molar Mass | 249.35 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Melting Point | 150 °C |
| Boling Point | 372.8±45.0 °C(Predicted) |
| pKa | -2.75±0.20(Predicted) |
| Storage Condition | 2-8°C |
| In vitro study | BTR-1 (10, 50, 100, and 250 µM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC 50 s of 8 and 6 µM at 48 and 72 h, respectively. Cell Viability Assay Cell Line: T-cell leukemic cell lines Concentration: 10, 50, 100, and 250 µM Incubation Time: 5 days Result: Induced cytotoxicity in human leukemic cells in a dose-dependent manner. |
3-Ethyl-5-benzylidene-2-thioxothiazolidin-4-one - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.01 ml | 20.052 ml | 40.104 ml |
| 5 mM | 0.802 ml | 4.01 ml | 8.021 ml |
| 10 mM | 0.401 ml | 2.005 ml | 4.01 ml |
| 5 mM | 0.08 ml | 0.401 ml | 0.802 ml |
Last Update：2024-01-02 23:10:35
3-Ethyl-5-benzylidene-2-thioxothiazolidin-4-one - Reference Information
| biological activity | BTR-1 is an active anticancer agent, which can induce cell cycle S phase arrest and affect DNA replication. BTR-1 can activate apoptosis (apoptosis), leading to cell death. |
| target | Apoptosis |
| in vitro study | BTR-1 (10, 50, 100, and 250 m, 5 days) dose-dependently cytotoxicity in human leukemic cells, with IC 50 s of 8 and 6 m at 48 and 72 h, respectively. Cell Viability Assay Cell Line: T-cell leukemic cell lines Concentration: 10, 50, 100, and 250 m Incubation Time: 5 days Result: induced cytotoxicity in human leukemic cells in a dose-dependent banner. |
| Cell Line: | T-cell leukemic cell lines |
| Concentration: | 10, 50, 100, and 250 µM |
| Incubation Time: | 5 days |
| Result: | Induced cytotoxicity in human leukemic cells in a dose-dependent manner. |
Last Update：2024-04-10 22:29:15
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View History
3-Ethyl-5-benzylidene-2-thioxothiazolidin-4-one
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