Name | 5-Cyano-2-hydroxypyridine |
Synonyms | 5-CYANO-2(1H)-PYRIDINONE 3-CYANO-6-HYDROXYPYRIDINE 5-CYANO-2-HYDROXYPYRIDINE 5-Cyano-2-hydroxypyridine 3-Cyano-6-hydroxypyridine 2-HYDROXY-5-CYANO PYRIDINE 6-hydroxypyridine-3-carbonitrile 6-oxo-1,6-dihydropyridine-3-carbonitrile 3-Pyridinecarbonitrile,1,6-dihydro-6-oxo-(9CI) 6-HYDROXYNICOTINONITRILE (3-CYANO-6-HYDROXY PYRIDINE) |
CAS | 94805-52-4 |
EINECS | 688-401-2 |
InChI | InChI=1/C6H4N2O/c7-3-5-1-2-6(9)8-4-5/h1-2,4H,(H,8,9) |
Molecular Formula | C6H4N2O |
Molar Mass | 120.11 |
Density | 1.27±0.1 g/cm3(Predicted) |
Melting Point | 256-258 |
Boling Point | 332.7±35.0 °C(Predicted) |
Flash Point | 155°C |
Vapor Presure | 0.000143mmHg at 25°C |
pKa | 8.67±0.10(Predicted) |
Storage Condition | Keep Cold |
Refractive Index | 1.571 |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
Hazard Note | Irritant/Keep Cold |
Hazard Class | IRRITANT |
Use | 3-cyano-6-hydroxypyridine belongs to pyridine derivatives, which are energetic precursors, frequently selected as raw material/mother core for the preparation of pharmaceutical and chemical products. |
preparation | with 6-chloropyridine-3-carboxamide as the starting material, the target compound 3-cyano-6-hydroxypyridine was obtained after preparation of cyano group and hydrolysis to form hydroxyl group. The synthesis reaction formula is shown below: |