Molecular Formula | C3H6ClNO2 |
Molar Mass | 123.54 |
Density | 1.2776 (rough estimate) |
Melting Point | 156 °C |
Boling Point | 243.6±30.0 °C(Predicted) |
Water Solubility | soluble |
Solubility | soluble |
Appearance | White crystalline powder |
Color | White to Off-White |
pKa | 1.89±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.5000 (estimate) |
In vitro study | β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
Reference Show more | 1. [IF=3.631] Baolei Liu et al."Local Photothermal/Photodynamic Synergistic Antibacterial Therapy Based on Two-dimensional BP@CQDs Triggered by Single NIR Light Source."Photodiagnosis and Photodynamic Therapy. 2022 May;:102905 |
Biological activity | β-Chloro-L-alanine is an inhibitory amino acid analog that inhibits a variety of enzymes, including threonine deaminase and alanine racemase. |
target | Bacterial |