3-CHLORO-4-FORMYLPYRIDINE
3-Chloropyridine-4-carboxaldehyde
CAS: 72990-37-5
Molecular Formula: C6H4ClNO
3-CHLORO-4-FORMYLPYRIDINE - Names and Identifiers
3-CHLORO-4-FORMYLPYRIDINE - Physico-chemical Properties
| Molecular Formula | C6H4ClNO |
| Molar Mass | 141.56 |
| Density | 1.332±0.06 g/cm3(Predicted) |
| Melting Point | 58-62°C(lit.) |
| Boling Point | 93°C/6mmHg(lit.) |
| Flash Point | 89.8°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.0888mmHg at 25°C |
| Appearance | Solid |
| Color | White to yellow |
| pKa | 0.97±0.18(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | 1.592 |
| MDL | MFCD06200712 |
3-CHLORO-4-FORMYLPYRIDINE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R43 - May cause sensitization by skin contact R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
3-CHLORO-4-FORMYLPYRIDINE - Introduction
It is an organic compound whose chemical formula is C6H4ClNO. The properties, use, preparation and safety information of the compound are given below:
Nature:
is a pale yellow to yellow liquid with a special weed-like odor. It has a density of 1.39g/cm³, a melting point of -6°C and a boiling point of 195-197°C. It can be dissolved in organic solvents such as ethanol, acetone and ether.
Use:
As an important chemical intermediate, it is widely used in the field of organic synthesis. It can be used as a raw material for pyridine antibiotics, pesticides and pharmaceutical intermediates. In addition, it can also be used to synthesize chemical fluorescent probes and dyes.
Preparation Method:
There are many ways to prepare the calcium salt. One of the commonly used methods is the oxidative coupling of 3-chloropyridine and formaldehyde. Specifically, 3-chloropyridine can be reacted with sodium acetate to form sodium 3-chloropyridine-4-formate, and then converted to pyridinium by acidolysis.
Safety Information:
It is an organic compound that is irritating and corrosive. Take proper precautions during handling and use to avoid contact with skin and eyes. If contact with skin or eyes occurs, rinse immediately with plenty of water and seek medical help. At the same time, it should be used in a well-ventilated place and away from fire and other flammable materials.
Nature:
is a pale yellow to yellow liquid with a special weed-like odor. It has a density of 1.39g/cm³, a melting point of -6°C and a boiling point of 195-197°C. It can be dissolved in organic solvents such as ethanol, acetone and ether.
Use:
As an important chemical intermediate, it is widely used in the field of organic synthesis. It can be used as a raw material for pyridine antibiotics, pesticides and pharmaceutical intermediates. In addition, it can also be used to synthesize chemical fluorescent probes and dyes.
Preparation Method:
There are many ways to prepare the calcium salt. One of the commonly used methods is the oxidative coupling of 3-chloropyridine and formaldehyde. Specifically, 3-chloropyridine can be reacted with sodium acetate to form sodium 3-chloropyridine-4-formate, and then converted to pyridinium by acidolysis.
Safety Information:
It is an organic compound that is irritating and corrosive. Take proper precautions during handling and use to avoid contact with skin and eyes. If contact with skin or eyes occurs, rinse immediately with plenty of water and seek medical help. At the same time, it should be used in a well-ventilated place and away from fire and other flammable materials.
Last Update：2024-04-09 21:11:58
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View History
3-CHLORO-4-FORMYLPYRIDINE
3-硝柳酸
OTAVA-BB BB7020410158
2-CYCLOPROPYL-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE
2-(3-氟苯氧基)-1-乙胺
1(S)-[1(R)-(DIMETHYLAMINO)ETHYL]-2-(DIPHENYL-PHOSPHANY)FERROCENE
Ethanol, 2-[(1-naphthalenylmethyl)thio]-
1-Bromo-3-chloropropane, [Trimethylene bromochloride]
TETRAMETHYLAMMONIUMHYDROXIDE,15%(W/W)SOLUTIONINPROPYLENEGLYCOL
N-[4-[2-(2-氨基-4,7-二氢-4-氧代-1H-吡咯并[2,3-D]嘧啶-5-基)乙基]苯甲酰基]-L-谷氨酸
3-硝柳酸
OTAVA-BB BB7020410158
2-CYCLOPROPYL-6-PHENYL-4-(TRIFLUOROMETHYL)NICOTINONITRILE
2-(3-氟苯氧基)-1-乙胺
1(S)-[1(R)-(DIMETHYLAMINO)ETHYL]-2-(DIPHENYL-PHOSPHANY)FERROCENE
Ethanol, 2-[(1-naphthalenylmethyl)thio]-
1-Bromo-3-chloropropane, [Trimethylene bromochloride]
TETRAMETHYLAMMONIUMHYDROXIDE,15%(W/W)SOLUTIONINPROPYLENEGLYCOL
N-[4-[2-(2-氨基-4,7-二氢-4-氧代-1H-吡咯并[2,3-D]嘧啶-5-基)乙基]苯甲酰基]-L-谷氨酸