3-(二甲基胺)-1-(3-甲氧苯基)-2-甲基-1-PROPANONE(TAPENTADOL中间体)

3-(二甲基胺)-1-(3-甲氧苯基)-2-甲基-1-PROPANONE(TAPENTADOL中间体) - Names and Identifiers

Name	3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone
Synonyms	-2-methylpropan-1-one 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-propanone 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one 3-(diMethylaMino)-1-(3-Methoxyphenyl)-2-Methylpropan-1-one 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone 1-Propanone,3-(diMethylaMino)-1-(3-Methoxyphenyl)-2-Methyl- 3-(dimethylamino)-l -(3-methoxyphenyl)-2-methyl-l -propanone 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone fandachem 3-(DIMETHYLAMINO)-1-(3-METHOXYPHENOL)-2-METHOXYPROPAN-1-ONE HYDROCHLORIDE
CAS	197145-37-2
InChI	InChI=1/C13H19NO2/c1-10(9-14(2)3)13(15)11-6-5-7-12(8-11)16-4/h5-8,10H,9H2,1-4H3

3-(二甲基胺)-1-(3-甲氧苯基)-2-甲基-1-PROPANONE(TAPENTADOL中间体) - Physico-chemical Properties

Molecular Formula	C13H19NO2
Molar Mass	221.3
Density	1.012g/cm³
Boling Point	315.8°C at 760 mmHg
Flash Point	144.8°C
Vapor Presure	0.000428mmHg at 25°C
Refractive Index	1.508

3-(二甲基胺)-1-(3-甲氧苯基)-2-甲基-1-PROPANONE(TAPENTADOL中间体) - Introduction

3-(dimethylinino)-1-(3-methyphenyl)-2-methyl-1-propanone, also known as DEMA-MOPA, is an organic compound. The following is a description of the nature, use, preparation and safety information of the DEMA-MOPA:

Nature:
-Appearance: White solid
-molecular formula: C15H19NO2
-Molecular weight: 245.32g/mol
-Melting point: 70-72 ° C
-Boiling point: 180-185 ° C
-Solubility: DEMA-MOPA can be dissolved in some organic solvents

Use:
- DEMA-MOPA are usually used as reagents and intermediates in organic synthesis reactions.
-It can be used to synthesize biologically active compounds, such as pharmaceutically active molecules.

Method:
- DEMA-MOPA can be prepared by the reaction of 3-methoxybenzoic acid and 2-methylacetone.
-The general steps are as follows:
1. Dissolve 3-methoxybenzoic acid in the reaction solvent and add a base (such as sodium hydride).
2. 2-Methylacetone was added and reacted.
3. After completion of the reaction, the product was purified by crystallization and dried.

Safety Information:
- DEMA-MOPA dust may be irritating to eyes and skin. Wear personal protective equipment when using.
-In the use or handling of DEMA-MOPA, should comply with the relevant dangerous goods operating procedures.
-storage should be sealed in a cool, dry place, avoid contact with air, moisture and high temperature.

Last Update：2024-04-09 02:00:44