Molecular Formula | C9H12BNO3 |
Molar Mass | 193.01 |
Density | 1.20±0.1 g/cm3(Predicted) |
Melting Point | 122-128°C |
Boling Point | 423.0±47.0 °C(Predicted) |
Flash Point | 209.6°C |
Solubility | slightly sol. in Methanol |
Vapor Presure | 6.56E-08mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
pKa | 7.94±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.553 |
Hazard Symbols | Xi - Irritant |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
Hazard Note | Irritant/Keep Cold |
Hazard Class | IRRITANT |
application | 3-dimethylaminophenylboronic acid can be used as an intermediate in organic synthesis and pharmaceutical, mainly used in laboratory research and development processes and chemical production processes. |
preparation | sodium hydroxide (5. 84g,146 mmol) is dissolved in 300 mL of water, p-methylphenylboronic acid (10. 00g,73 mmol) is added, and potassium permanganate (23. 05g,146 mmol) is slowly added in batches (500mL) solution. After adding, raise the temperature to 100 ℃ reflux, stir and react overnight. After the reaction is complete, cool to 50 ℃, add 200 mL of ethanol, filter to remove manganese dioxide, and concentrate the filtrate to 100 mL. Use hydrochloric acid to slowly adjust the concentrated solution to acidic, precipitate to form, filter, wash the filter cake with a small amount of water and recrystallize with water to obtain colorless solid 4-carboxyphenylboronic acid (10. 30g,85%). |