3,5-Di(trifluoromethyl)-1H-pyrazole - Names and Identifiers
3,5-Di(trifluoromethyl)-1H-pyrazole - Physico-chemical Properties
Molecular Formula | C5H2F6N2
|
Molar Mass | 204.07 |
Density | 1.5672 (estimate) |
Melting Point | 83-85°C(lit.) |
Boling Point | 147°C(lit.) |
Solubility | soluble in Methanol |
Appearance | powder to crystal |
Color | White to Almost white |
pKa | 7.12±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Physical and Chemical Properties | WGK Germany:3 |
3,5-Di(trifluoromethyl)-1H-pyrazole - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
3,5-Di(trifluoromethyl)-1H-pyrazole - Introduction
3,5-bis (TRIFLUOROMETHYL)PYRAZOLE is an organic compound with the chemical formula C7H2F6N2. The following is a description of its nature, use, formulation and safety information:
1. Nature:
3,5-bis (TRIFLUOROMETHYL)PYRAZOLE has the form of a colorless crystalline solid with a melting point of about 90-92°C. It is soluble in polar organic solvents such as methylene chloride, ethanol and dimethylformamide, and practically insoluble in water. It is less stable to the environment of nature, so it needs to be used and handled carefully.
2. Use:
3,5-bis (TRIFLUOROMETHYL)PYRAZOLE is often used as a catalyst or ligand in organic synthesis. It can act as a fluorinating, reducing or oxidizing agent in many organic reactions. These reactions include C- H bond activation of aromatic compounds, fluorination of alkenes and alkynes, etc.
3. Preparation method:
3,5-bis (TRIFLUOROMETHYL)PYRAZOLE is generally prepared by the reaction of dihydrourea with trifluoroformic acid. First, dihydrourea is reacted with trifluoroformic acid to form 3,5-bis (trifluoromethyl) urea under the catalysis of a base. Subsequently, the urea was decomposed by further treatment with hydrogen peroxide to give 3,5-bis (TRIFLUOROMETHYL)PYRAZOLE.
4. Safety Information:
3,5-bis (TRIFLUOROMETHYL)PYRAZOLE is generally safer when used and stored correctly. However, it is an organic compound, so care needs to be taken to avoid contact with skin and eyes, and to maintain good ventilation conditions. At the same time, contact with flammable substances or oxidizing agents should be avoided. During handling and transportation, appropriate protective measures should be taken and relevant safety procedures should be observed.
Last Update:2024-04-10 22:29:15