3,4-Dimethoxyphenylacetylene - Names and Identifiers
Name | 4-ethynyl-1,2-dimethoxybenzene
|
Synonyms | 3,4-Dimethoxyphenylacetylene 4-ethynyl-1,2-dimethoxybenzene 1,2-Dimethoxy-4-ethynylbenzene 4-ETHYNYL-1,2-DIMETHOXY-BENZENE 3',4'-Dimethoxyphenyl acetylene 1-ETHYNYL-3,4-DIMETHOXY-BENZENE 3',4'-DIMETHOXYPHENYL ACETYLENE Benzene, 4-ethynyl-1,2-dimethoxy- Benzene, 4-ethynyl-1,2-diMethoxy-
|
CAS | 4302-52-7
|
InChI | InChI=1/C10H10O2/c1-4-8-5-6-9(11-2)10(7-8)12-3/h1,5-7H,2-3H3 |
3,4-Dimethoxyphenylacetylene - Physico-chemical Properties
Molecular Formula | C10H10O2
|
Molar Mass | 162.19 |
Density | 1.06±0.1 g/cm3(Predicted) |
Melting Point | 76℃ |
Boling Point | 130℃ |
Flash Point | 88.1°C |
Vapor Presure | 0.079mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | 1.522 |
3,4-Dimethoxyphenylacetylene - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
3,4-Dimethoxyphenylacetylene - Introduction
4-ethynyl-1,2-dimethoxybenzene(4-ethynyl-1,2-dimethoxybenzene) is an organic compound whose chemical formula is C10H10O2. Here are some of its properties and uses:
Nature:
-Appearance: 4-ethynyl-1,2-dimethoxybenzene is a colorless to light yellow crystal or powdery substance.
-Solubility: It can be dissolved in organic solvents such as ethanol, dichloromethane and chloroform, but it is insoluble in water.
-Melting point: Its melting point is about 50-52°C.
-Stability: 4-ethynyl-1,2-dimethoxybenzene is relatively stable at room temperature, but decomposition reaction may occur under high temperature conditions.
Use:
-Chemical synthesis: 4-ethynyl-1,2-dimethoxybenzene can be used in organic synthesis reactions, for example, as a functional group in the synthesis of fluorescent dyes or organic molecules.
-Pharmaceutical field: The compound has certain application potential in certain drug research, such as as precursors and intermediates of anti-cancer drugs.
Preparation Method:
4-ethynyl-1,2-dimethoxybenzene can be prepared by the following steps:
1. The reaction of p-methanol phenol (1,2-dihydroxybenzene) with alkali solution generates p-cresol phenol ether (1,2-dimethoxybenzene).
2. Then, 4-ethynyl-1,2-dimethoxybenzene was obtained by the reaction of iodination and iodinated phenethyl alcohol (4-ethynylphenol).
Safety Information:
When dealing with 4-ethynyl-1,2-dimethoxybenzene, you need to pay attention to the following safety precautions:
-It is recommended to wear appropriate personal protective equipment, such as laboratory gloves, protective glasses and laboratory coats.
-Avoid inhaling its dust or vapor, and operate in a well-ventilated area.
-Avoid contact with skin and eyes. If so, rinse immediately with plenty of water and seek medical help.
-Since 4-ethynyl-1,2-dimethoxybenzene has no clear toxicity data available, its potential risks to the human body and the environment should be taken into account, and safe operating procedures should be followed. It is best to operate in an experienced chemical laboratory or specialized premises.
Last Update:2024-04-09 21:32:41