3,4,5-Trifluorobenzyl
3,4,5-(trifluorophenyl)acetonitrile
CAS: 220228-03-5
Molecular Formula: C8H4F3N
3,4,5-Trifluorobenzyl - Names and Identifiers
3,4,5-Trifluorobenzyl - Physico-chemical Properties
| Molecular Formula | C8H4F3N |
| Molar Mass | 171.12 |
| Density | 1.334±0.06 g/cm3(Predicted) |
| Melting Point | 30-32°C |
| Boling Point | 214.1±35.0 °C(Predicted) |
| Flash Point | 83.3°C |
| Vapor Presure | 0.159mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.468 |
| MDL | MFCD00083531 |
3,4,5-Trifluorobenzyl - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 3276 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | III |
3,4,5-Trifluorobenzyl - Introduction
3,4,5-(trifluorophenyl)acetonitril is an organic compound with the chemical formula C8H4F3N. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance: colorless liquid or solid.
2. Melting Point: about 30-32 ° C.
3. Boiling Point: about 135-136 ° C.
4. Density: About 1.37 g/cm.
5. Solubility: Soluble in some organic solvents, such as alcohols, ethers and chlorinated hydrocarbons.
Use:
1. 3,4,5-(trifluorophenyl)acetonitril can be used as a reagent or intermediate in organic synthesis.
2. It also has some applications in the field of medicine, such as for the preparation of drugs, pesticides and so on.
Method: A common preparation method of
3,4,5-(trifluorophenyl)acetonitril is as follows:
First, 3,4, 5-trifluorobenzaldehyde and sodium cyanide are added to the reaction bottle, and the reaction is carried out under alkaline conditions. After completion of the reaction, the intermediate product may be acidified with an acid etchant to obtain the target product.
Safety Information:
1. 3,4,5-(trifluorophenyl)acetonitril may be irritating and corrosive, and care should be taken when in contact with eyes, skin and respiratory tract.
2. In the process of operation, should wear appropriate protective gloves, protective glasses and protective clothing.
3. When exposed to the compound, rinse immediately with plenty of water and seek medical help if necessary.
Nature:
1. Appearance: colorless liquid or solid.
2. Melting Point: about 30-32 ° C.
3. Boiling Point: about 135-136 ° C.
4. Density: About 1.37 g/cm.
5. Solubility: Soluble in some organic solvents, such as alcohols, ethers and chlorinated hydrocarbons.
Use:
1. 3,4,5-(trifluorophenyl)acetonitril can be used as a reagent or intermediate in organic synthesis.
2. It also has some applications in the field of medicine, such as for the preparation of drugs, pesticides and so on.
Method: A common preparation method of
3,4,5-(trifluorophenyl)acetonitril is as follows:
First, 3,4, 5-trifluorobenzaldehyde and sodium cyanide are added to the reaction bottle, and the reaction is carried out under alkaline conditions. After completion of the reaction, the intermediate product may be acidified with an acid etchant to obtain the target product.
Safety Information:
1. 3,4,5-(trifluorophenyl)acetonitril may be irritating and corrosive, and care should be taken when in contact with eyes, skin and respiratory tract.
2. In the process of operation, should wear appropriate protective gloves, protective glasses and protective clothing.
3. When exposed to the compound, rinse immediately with plenty of water and seek medical help if necessary.
Last Update：2024-04-09 21:01:54
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View History
3,4,5-Trifluorobenzyl
2H-1,4-Benzoxazin-3(4H)-one, 8-Methyl-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
4-[(5Z)-5-({3-[4-(butylsulfanyl)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid
7-Chloro-4-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid
ZINC01440341
Acrylate pressure sensitive adhesive,latex type,medical use
181145-44-8
Dibenzofuran, 1,2,3,8-tetrachloro-
N-(5-bromo-2-pyridinyl)-4-(4-ethoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxamide
3-Pyridinol,6-chloro-2-nitro-
2H-1,4-Benzoxazin-3(4H)-one, 8-Methyl-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
4-[(5Z)-5-({3-[4-(butylsulfanyl)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid
7-Chloro-4-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid
ZINC01440341
Acrylate pressure sensitive adhesive,latex type,medical use
181145-44-8
Dibenzofuran, 1,2,3,8-tetrachloro-
N-(5-bromo-2-pyridinyl)-4-(4-ethoxyphenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxamide
3-Pyridinol,6-chloro-2-nitro-