Name | Loganetin |
Synonyms | Loganol Loganetin Loganigenin Loganigenine Loganin aglycon Loganin aglycone Loganoside aglycon Loganetin - Menyanthes trifoliata (bogbean) |
CAS | 29748-10-5 |
Molecular Formula | C11H16O5 |
Molar Mass | 228.24 |
Density | 1.307±0.06 g/cm3(Predicted) |
Boling Point | 375.7±42.0 °C(Predicted) |
Specific Rotation(α) | ?24 (EtOH) |
pKa | 12.12±0.70(Predicted) |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Oily liquid, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Cornus Cornus officinalis Sieb. et Zucc.. |
In vitro study | Although Loganetin does not possess antibacterial activity of its own, but in combination, it appreciably reduces the minimum inhibitory concentration (MIC) of nalidixic acid (NA) against nalidixic acid resistant (NAREC) and nalidixic acid sensitive (NASEC) strains of Escherichia coli . Loganetin, a very common, inexpensive, and non-toxic natural product may finds its application in the antibacterial drug development for treating multidrug-resistant Gram negative infections. |
biological activity | Loganetin is a non-toxic natural product that can be used in the study of multi-drug resistant gram-negative bacterial infections. |