Name | Glutathione EP Impurity D (TFA Salt) |
Synonyms | γ-glutamylcysteine (TFA) Gamma-glutamylcysteine (TFA) Glutathione EP Impurity D (TFA Salt) Glutathione EP Impurity D Trifluoroacetate |
CAS | 283159-88-6 |
Molecular Formula | C20H32N6O12S2 |
Molar Mass | 612.63108 |
Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated) |
Appearance | Solid |
Color | White to Off-White Sticky to |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Stability | Unstable in Solution |
biological activity | Gamma-glutamylcysteine (gamma-glutaminyl cysteine) TFA is an intermediate in the synthesis of glutathione (GSH), A dipeptide that is an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA up-regulates the levels of anti-inflammatory cytokines IL-10, reduces the levels of pro-inflammatory cytokines (TNF-α,IL-6 and IL-1β), and attenuates changes in metalloprotease activity in oligo-Aβ40 treated astrocytes. |