Fmoc-(S)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric is an organic compound with the following properties: It is a white crystalline powder in appearance, its chemical formula is C21H17F3NO3, and its relative molecular mass is 399.36g/mol. It has good solubility and is soluble in organic solvents such as dimethyl sulfoxide (DMSO), chloroform and dichloromethane.
Fmoc-(S)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid is commonly used in polypeptide synthesis and solid phase synthesis reactions in organic synthesis. As a protecting group in the synthesis of peptide fragments, it can be used to protect α-amino acids from unnecessary reactions. It is widely used in the field of biomedical research, such as peptide synthesis, drug design and biological activity research.
the method for preparing Fmoc-(S)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid is relatively simple. usually, the target product can be obtained by first reacting S-3-amino -4-(4-trifluoromethylphenyl) butyric acid and Fmoc-Cl for acylation, and then purifying by crystallization.
Regarding safety information, Fmoc-(S)-3-Amino-4-(4-trifluoromethyl-phenyl)-butyric acid is generally not significantly toxic or hazardous under normal operating conditions. But as an organic compound, it still needs to be careful to avoid inhalation, contact with the skin and enter the eyes. Wear appropriate personal protective equipment during use or operation, ensure good indoor ventilation, and take appropriate chemical protection measures as needed.