270063-49-5 - Names and Identifiers
Name | Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid
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Synonyms | RARECHEM AK PT F041 Fmoc-β-HoPhe(2,4-DiCl)-OH Fmoc-b-HoPhe(2,4-DiCl)-OH Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid (S)-3-(Fmoc-amino)-4-(2,4-dichlorophenyl)butyric acid (9H-Fluoren-9-yl)MethOxy]Carbonyl (S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2,4-dichlorophenyl)butanoic acid (3S)-4-(2,4-dichlorophenyl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid FMoc-2,4-dichloro-L-β-hoMophenylalanine FMoc-(S)-3-aMino-4-(2,4-dichlorophenyl)butyric acid
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CAS | 270063-49-5
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270063-49-5 - Physico-chemical Properties
Molecular Formula | C25H21Cl2NO4
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Molar Mass | 470.34 |
Density | 1.367±0.06 g/cm3(Predicted) |
Boling Point | 672.3±55.0 °C(Predicted) |
pKa | 4.30±0.10(Predicted) |
Storage Condition | 2-8°C |
270063-49-5 - Risk and Safety
270063-49-5 - Introduction
Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid is a commonly used reagent in organic synthesis, which has certain properties and uses.
Nature:
Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid is a white or off-white solid with a high melting point. It is an acidic compound, soluble in organic solvents such as dimethyl sulfoxide and methylene chloride, and soluble in organic solvents under alkaline conditions such as acetonitrile.
Use:
Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid is mainly used for peptide synthesis in solid phase synthesis. By reacting with other amino acids or polypeptide fragments, it can be introduced into the target molecule and used to construct a specific peptide chain structure.
Preparation Method:
The synthesis of Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid usually involves a multi-step reaction. A common preparation method is to use succinic acid as a starting material, through esterification, ozonation and other steps, and then through the synthesis of amino acids to introduce Fmoc protection groups, and finally produce the target product.
Safety Information:
Fmoc-(S)-3-Amino-4-(2,4-dichloro-phenyl)-butyric acid is generally relatively safe under normal operating conditions. However, as a chemical agent, it may have a certain irritation and toxicity. Proper laboratory practices should be followed when using the compound, including wearing appropriate protective equipment (e. g. gloves, glasses, laboratory coats), ensuring that the compound is operated in a well-ventilated environment and avoiding direct contact with skin, eyes, etc. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help if necessary.
Last Update:2024-04-09 20:45:29