S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
WGK Germany
3
FLUKA BRAND F CODES
10
Hazard Class
IRRITANT
269398-87-0 - Introduction
Fmoc-(R)-3-Amino-5-phenyl-pentanoic acid is an organic compound commonly used in solid-phase synthesis. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Generally white to light yellow solid.
-Molecular formula: C24H21NO4
-Molecular weight: 383.43g/mol
-Melting point: about 110-115 degrees Celsius
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane and ethanol.
Use:
Fmoc-(R)-3-Amino-5-phenyl-pentanoic acid is mainly used as a protecting group in peptide synthesis to protect the amino (-NH2) functional group in amino acid molecules to prevent non-specific reactions during synthesis. After synthesis and purification, non-protected amino acids can be obtained by removal of the Fmoc protecting group.
Preparation Method:
The preparation of Fmoc-(R)-3-Amino-5-phenyl-pentanoic acid generally involves a multi-step reaction. The specific steps may vary depending on the preparation method. A common method of preparation is to synthesize the compound by attaching an Fmoc protecting group to (R)-3-amino-5-phenylpentanoic acid.
Safety Information:
Fmoc-(R)-3-Amino-5-phenyl-pentanoic acid is generally a chemical and should follow routine laboratory practices and safe operating procedures. Take care to avoid inhalation, ingestion or contact with skin and eyes. Appropriate personal protective equipment should be worn during use to ensure that the operation is carried out in a well-ventilated environment. If exposed or taken by mistake, seek medical attention immediately.