24082-11-9 - Names and Identifiers
24082-11-9 - Physico-chemical Properties
Molecular Formula | C8H20O2Si2
|
Molar Mass | 204.41 |
Density | 0.867g/mLat 25°C(lit.) |
Boling Point | 61°C10mm Hg(lit.) |
Flash Point | 118°F |
Vapor Presure | 2.07mmHg at 25°C |
Storage Condition | 0-6°C |
Refractive Index | n20/D 1.417(lit.) |
24082-11-9 - Risk and Safety
Risk Codes | 10 - Flammable
|
Safety Description | S16 - Keep away from sources of ignition.
S36 - Wear suitable protective clothing.
|
UN IDs | UN 3272 3/PG 3 |
WGK Germany | 3 |
24082-11-9 - Introduction
trimethylsilyl (trimethylsilyl)acetate is an organosilicon compound with the chemical formula [(CH3)3SiO][O] cch3. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: trimethylsilyl (trimethylsilyl)acetate is a colorless to pale yellow liquid.
-Solubility: It is soluble in organic solvents such as ethers, alcohols and aromatic hydrocarbons, but almost insoluble in water.
-Melting point: About -80 ° C.
-Thermal stability: trimethylsilyl (trimethylsilyl)acetate can be decomposed at high temperature.
Use:
-as a protective group: trimethylsilyl (trimethylsilyl)acetate can be used as a protective group in organic synthesis to protect compounds composed of active hydroxyl, carboxyl and other functional groups, to avoid its undesirable reaction under certain reaction conditions.
-As an organosilicon reagent: It can be used as a reagent in organic synthesis to participate in a series of reactions such as esterification of carboxylic acids, Grignard reactions of aldehydes and ketones, etc.
Method:
The method for preparing trimethylsilyl acetate is generally obtained by reacting trimethylsilyl chloroacetate with trimethylsilanol. The reaction is usually carried out under inert gas protection.
Safety Information:
- trimethylsilyl (trimethylsilyl)acetate is a chemical that should be handled in accordance with proper laboratory safety procedures.
-Avoid contact with strong oxidants and strong acids.
-Be equipped with appropriate protective measures during operation, such as gloves, laboratory coat and goggles.
-For unintended contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-10 22:29:15