Name | 5-bromo-1-benzofuran |
Synonyms | 5-BROMOBENZOFURAN 5-bromo benzofuran 5-Bromo-benzofuran 5-bromo-1-benzofuran 5-BROMO-1-BENZOFURAN 5-Bromobenzo[b]furan Benzofuran, 5-broMo- 5-BROMOBENZO[BETA]FURAN 5-Bromobenzo[beta]furan |
CAS | 23145-07-5 |
InChI | InChI=1/C8H5BrO/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5H |
Molecular Formula | C8H5BrO |
Molar Mass | 197.03 |
Density | 1.573 g/mL at 25 °C |
Melting Point | 8°C(lit.) |
Boling Point | 226°C(lit.) |
Flash Point | 95.2°C |
Vapor Presure | 0.0835mmHg at 25°C |
Appearance | Colorless to light yellow liquid |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D1.605 |
MDL | MFCD03407317 |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
HS Code | 29329990 |
Hazard Note | Irritant |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
overview | benzofurans and their derivatives such as 5-bromobenzofurans are very important organic compounds with high biological activity and widely exist in many natural product skeletons, so the synthesis of benzofurans and their derivatives has received extensive attention. Traditional methods have played an important role in the synthesis of biologically active benzofurans, but there are widespread problems such as long routes, harsh substrate and reaction conditions, and limited expansion of substitution functional groups. Palladium and other precious metals as catalysts to synthesize benzofurans can overcome the shortcomings of traditional synthesis methods, and the yield has been further improved, but the cost is higher. |