Name | 4,4-dimethyl-2-cyclopenten-1-one |
Synonyms | 4,4-dimethylcyclopent-2-enone 4,4-DIMETHYL-2-CYCLOPENTEN-1-ONE 4,4-Dimethyl-2-cyclopenten-1-one 4,4-dimethyl-2-cyclopenten-1-one 4,4-dimethylcyclopent-2-en-1-one 2-Cyclopenten-1-one, 4,4-dimethyl- |
CAS | 22748-16-9 |
InChI | InChI=1/C7H10O/c1-7(2)4-3-6(8)5-7/h3-4H,5H2,1-2H3 |
Molecular Formula | C7H10O |
Molar Mass | 110.15 |
Density | 0.903 g/mL at 25 °C (lit.) |
Melting Point | 174-175 °C |
Boling Point | 158 °C (lit.) |
Flash Point | 115°F |
Vapor Presure | 3.09mmHg at 25°C |
Storage Condition | 2-8℃ |
Refractive Index | n20/D 1.457(lit.) |
In vitro study | 4,4-Dimethyl-2-cyclopenten-1-one selectively kills the tumor cells (HSC-2, HL-60). 4,4-Dimethyl-2-cyclopenten-1-one exhibits CC 50 (50% cytotoxic concentration) values of 43.8 μg/mL, 152 μg/mL, 118 μg/mL, 14.0 μg/mL, 177 μg/mL and 123 μg/mL in HSC-2, HSC-3, HSG, HL-60, HGF and normal cells (HPC), respectively. |
Risk Codes | 10 - Flammable |
Safety Description | 16 - Keep away from sources of ignition. |
UN IDs | UN 1224 3/PG 3 |
WGK Germany | 3 |
Hazard Class | 3.2 |
Packing Group | III |
biological activity | 4,4-Dimethyl-2-cyclopenten-1-one is a natural product that can be derived from Apocyniveneti Folium and shows highly selective cytotoxicity to different tumor cells. |