223725-09-5 - Names and Identifiers
Name | (RP,R′P)-1,1′-Bis[(S)-α-(dimethylamino)benzyl]-2,2′-bis(diphenylphosphino)ferrocene
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Synonyms | (RP,R′P)-1,1′-Bis[(S)-α-(dimethylamino)benzyl]-2,2′-bis(diphenylphosphino)ferrocene (RP,RμP)-1,1μ-Bis[(S)-α-(dimethylamino)benzyl]-2,2μ-bis(diphenylphosphino)ferrocene 1,1'-bis[(R)-dimethylamino)phenylmethyl]-2,2'-(S,S)-bis(diphenyldiphosphino)-ferrocene
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CAS | 223725-09-5
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223725-09-5 - Physico-chemical Properties
223725-09-5 - Risk and Safety
WGK Germany | 3 |
HS Code | 29319090 |
223725-09-5 - Introduction
(RP,R′P)-1,1 ′-Bis[(S)-α-(dimethylamino)benzyl]-2,2 ′-bis(diphenylphosphino)ferrocene is an organic transition metal compound having the chemical formula [C44H42FeN2P2] and a molecular weight of 684.68g/mol.
The compound has the following properties:
1. Appearance: reddish brown crystal powder;
2. melting point: 205-215 ℃;
3. Solubility: Soluble in common organic solvents (such as chloroform, methanol, dimethylformamide).
The (RP,R′P)-1,1 ′-Bis[(S)-α-(dimethylamino)benzyl]-2,2 ′-bis(diphenylphosphino)ferrocene has the following main uses:
1. Chiral ligands of o-nitrobenzylamine and related compounds: As ligands of iron and other transition metal catalysts, it is widely used in asymmetric catalytic reactions in organic synthesis, especially the synthesis of o-nitrobenzylamine;
2. metal catalytic reaction catalyst: with palladium or platinum and other transition metal complexes, used to catalyze a variety of organic synthesis reactions, such as hydrogenation, isomerization and asymmetric catalytic reactions.
The method for preparing (RP,R′P)-1,1 ′-Bis[(S)-α-(dimethylamino)benzyl]-2,2 ′-bis(diphenylphosphino)ferrocene is usually carried out by the following steps:
1. reacting dimethylaminophenyl bromide with diphenylphosphino lithium to obtain the corresponding benzylphosphine compound;
2. A benzylphosphine compound is reacted with ferrocene halide to obtain (RP,R′P)-1,1 ′-Bis[(S)-α-(dimethylamino)benzyl]-2,2 ′-bis(diphenylphosphino)ferrocene.
Safety information regarding the (RP,R′P)-1,1 ′-Bis[(S)-α-(dimethylamino)benzyl]-2,2 ′-bis(diphenylphosphino)ferrocene, due to its low toxicity and no reported significant risk. However, as a compound, it should generally follow the safe practice of chemical laboratories, including wearing appropriate protective gloves and goggles to avoid inhalation of dust or contact with skin. During handling and storage, it should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
Last Update:2024-04-10 22:29:15