2-羟甲基-3-三氟甲基吡啶

2-羟甲基-3-三氟甲基吡啶 - Names and Identifiers

Name	(3-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
Synonyms	CHEMPACIFIC 38177 2-Pyridinemethanol, 3-(trifluoromethyl)- (3-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL [3-(trifluoromethyl)pyridin-2-yl]methanol 2-HYDROXYMETHYL-3-TRIFLUOROMETHYL-PYRIDINE
CAS	131747-44-9
InChI	InChI=1/C7H6F3NO/c8-7(9,10)5-2-1-3-11-6(5)4-12/h1-3,12H,4H2

2-羟甲基-3-三氟甲基吡啶 - Physico-chemical Properties

Molecular Formula	C7H6F3NO
Molar Mass	177.12
Density	1.362±0.06 g/cm3(Predicted)
Boling Point	201.4±35.0 °C(Predicted)
Flash Point	75.6°C
Vapor Presure	0.189mmHg at 25°C
pKa	12.88±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.462

2-羟甲基-3-三氟甲基吡啶 - Introduction

3-Trifluoromethylpyridine-2-methanol is an organic compound with the chemical formula C7H4F3NO and a molecular weight of 171.10g/mol. The following is its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Trifluoromethylpyridine-2-methanol is a colorless to pale yellow crystalline solid.
-Solubility: Soluble in water and organic solvents (such as ethanol, dimethylformamide).
-Melting point: about 60-63°C.
-Stability: It is relatively stable at room temperature, but may produce flammable gas under the action of strong oxidants.

Use:
-3-Trifluoromethylpyridine-2-methanol is commonly used as a substrate or intermediate in organic synthesis.
-It has important applications in drug synthesis, pesticide synthesis, dye synthesis and other fields.

Preparation Method:
The preparation of-3-trifluoromethylpyridine-2-methanol is usually obtained by reacting 1-trifluoromethylpyridine with methanol. The reaction conditions can be catalyzed by acid or by Lewis acid.

Safety Information:
-3-Trifluoromethylpyridine-2-methanol is irritating and may cause irritation to the eyes, skin and respiratory tract. Immediately after contact, rinse with plenty of water and seek medical advice.
-During the operation, attention should be paid to prevent inhalation, swallowing or skin absorption, and avoid prolonged contact.
-The product should be stored in a dry and ventilated place to avoid high temperature and fire.

Last Update：2024-04-09 15:17:51