2-甲基-4,6-二羟基-5-硝基嘧啶

2-甲基-4,6-二羟基-5-硝基嘧啶 - Names and Identifiers

Name	2-METHYL-5-NITRO-PYRIMIDINE-4,6-DIOL
Synonyms	2-Methyl-5-nitro-4,6-pyrimidinediol 2-METHYL-5-NITRO-PYRIMIDINE-4,6-DIOL 4,6-dihydroxy-2-methyl-5-nitropyrimidine 2-Methyl-4,6-dihydroxy-5-nitropyrimidine 2-Methyl-5-nitro-4,6-dihydroxypyrimidine 6-hydroxy-2-methyl-5-nitro-3H-pyrimidin-4-one 6-hydroxy-2-methyl-5-nitro-4(3H)-pyrimidinone 6-Hydroxy-2-methyl-5-nitro-4(1H)-pyrimidinone
CAS	53925-27-2

2-甲基-4,6-二羟基-5-硝基嘧啶 - Physico-chemical Properties

Molecular Formula	C5H5N3O4
Molar Mass	171.11
Density	1.84
Melting Point	270-280℃
pKa	1.71±0.10(Predicted)

2-甲基-4,6-二羟基-5-硝基嘧啶 - Introduction

6-DIOL is a chemical substance with the molecular formula C6H6N4O4 and a relative molecular mass of 198.14. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: 6-DIOL is a colorless crystalline powder.
-Solubility: It is soluble in water, alcohols and some organic solvents.
-Melting point: About 220-224 degrees Celsius.
-Stability: The compound is relatively stable at room temperature.

Use:
-Chemical reagents: 6-DIOL can be used as organic synthesis intermediates and chemical reagents, and has a wide range of applications in the field of organic chemistry and medicine.
-Drug synthesis: It can be used to synthesize a variety of drugs, including antibiotics, anti-cancer drugs and antiviral drugs.

Method:
The preparation of 6-DIOL can usually be carried out by the following steps:
1. First, 2-acetyl-5-nitro-4,6-pyrimidine (2-acetyl-5-nitro-4,6-dimethylpyrimidine) was reacted with NaOH to give 2-acetomethyl-5-nitro-4, 6-pyrimidine (2-acetyl-5-nitro-4,6-dimethyl-1,3-diazine).
2. Then, reduce it to 6-DIOL, and use a reducing agent (such as Sodium phosphite or sodium sulfite) for reaction.

Safety Information:
-, 6-DIOL is usually relatively safe under normal use conditions, but as a chemical substance, you still need to pay attention to the following:
-Avoid inhalation or contact with skin and eyes.
-Appropriate personal protective equipment should be used during use, such as laboratory gloves and protective glasses.
-The compound should be handled in a well-ventilated area.
-should be stored in a dry, cool and ventilated place, and away from fire and flammable materials.
-When exposed to the compound, rinse with plenty of water and seek medical advice.

Last Update：2024-04-09 21:01:54