2-氯-5-甲酰基-3-甲基吡啶
3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-
CAS: 176433-43-5
Molecular Formula: C7H6ClNO
2-氯-5-甲酰基-3-甲基吡啶 - Names and Identifiers
2-氯-5-甲酰基-3-甲基吡啶 - Physico-chemical Properties
| Molecular Formula | C7H6ClNO |
| Molar Mass | 155.58 |
| Density | 1.269±0.06 g/cm3(Predicted) |
| Melting Point | 51-53° |
| Boling Point | 269.2±35.0 °C(Predicted) |
| pKa | -1.24±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-氯-5-甲酰基-3-甲基吡啶 - Risk and Safety
| Hazard Class | IRRITANT |
2-氯-5-甲酰基-3-甲基吡啶 - Introduction
3-Pyridinecarboxaldehyde, 6-choro-5-methyll-, chemical formula C7H5ClNO2, molecular weight of 171.57g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance: 3-Pyridinecarboxaldehyde, 6-chroo-5-methyl-is a colorless crystalline solid.
2. Melting point: About 120°C to 122°C.
3. Boiling point: About 335 ℃.
4. Insoluble in water, but soluble in organic solvents such as ether and alcohol solvents.
Use:
1. 3-Pyridinecarboxaldehyde, 6-choro-5-methyl-can be used as an intermediate in organic synthesis and can be used to synthesize other organic compounds.
2. In the field of pharmaceutical chemistry, the compound can be used to synthesize pyrrolidine phenols, which have anti-inflammatory, antibacterial and anti-tumor activities.
Method:
The synthesis method of 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-is generally as follows:
1. Dissolve 5-methyl pyridine-3-carboxaldehyde in an ethanol solution of cuprous chloride (CuCl2).
2. Add aluminum chloride (AlCl3) solution Dropwise at low temperature, and the reaction generates 3-Pyridinecarboxaldehyde, 6-chloro-5-methyll-.
3. The mixture was filtered to give the product as a solid.
Safety Information:
1. 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-may be irritating to eyes, skin and respiratory tract, please avoid direct contact.
2. During Operation should wear protective gloves, protective glasses and respiratory protection equipment.
3. If accidentally come into contact with the substance, should immediately rinse with plenty of water, and medical treatment.
4. The compound should be stored in a dry, cool, well-ventilated place, away from fire and oxidizing agents.
5. When disposing of waste, please comply with local environmental regulations and dispose of it in accordance with correct waste disposal methods.
Nature:
1. Appearance: 3-Pyridinecarboxaldehyde, 6-chroo-5-methyl-is a colorless crystalline solid.
2. Melting point: About 120°C to 122°C.
3. Boiling point: About 335 ℃.
4. Insoluble in water, but soluble in organic solvents such as ether and alcohol solvents.
Use:
1. 3-Pyridinecarboxaldehyde, 6-choro-5-methyl-can be used as an intermediate in organic synthesis and can be used to synthesize other organic compounds.
2. In the field of pharmaceutical chemistry, the compound can be used to synthesize pyrrolidine phenols, which have anti-inflammatory, antibacterial and anti-tumor activities.
Method:
The synthesis method of 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-is generally as follows:
1. Dissolve 5-methyl pyridine-3-carboxaldehyde in an ethanol solution of cuprous chloride (CuCl2).
2. Add aluminum chloride (AlCl3) solution Dropwise at low temperature, and the reaction generates 3-Pyridinecarboxaldehyde, 6-chloro-5-methyll-.
3. The mixture was filtered to give the product as a solid.
Safety Information:
1. 3-Pyridinecarboxaldehyde, 6-chloro-5-methyl-may be irritating to eyes, skin and respiratory tract, please avoid direct contact.
2. During Operation should wear protective gloves, protective glasses and respiratory protection equipment.
3. If accidentally come into contact with the substance, should immediately rinse with plenty of water, and medical treatment.
4. The compound should be stored in a dry, cool, well-ventilated place, away from fire and oxidizing agents.
5. When disposing of waste, please comply with local environmental regulations and dispose of it in accordance with correct waste disposal methods.
Last Update：2024-04-09 02:00:43
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View History
2-氯-5-甲酰基-3-甲基吡啶
月桂醇聚醚磺基琥珀酸酯二钠
2-Chloro-1-(4-fluorophenyl)ethanone
2-氨基-3-氯-5-三氟甲基吡啶
(3-吡咯-1-基苯基)甲胺
Titanium tris (dodecylbenzenesulfonate) isopropoxide
2-羟基-2-(吡啶-3-基)乙酰胺
5-氯-4-硝基噻吩-2-甲酸甲酯
3-氨基-5-羟基吡啶二盐酸盐
2-氧代-7-氮杂螺[3.5]壬烷-7-甲酸叔丁酯
月桂醇聚醚磺基琥珀酸酯二钠
2-Chloro-1-(4-fluorophenyl)ethanone
2-氨基-3-氯-5-三氟甲基吡啶
(3-吡咯-1-基苯基)甲胺
Titanium tris (dodecylbenzenesulfonate) isopropoxide
2-羟基-2-(吡啶-3-基)乙酰胺
5-氯-4-硝基噻吩-2-甲酸甲酯
3-氨基-5-羟基吡啶二盐酸盐
2-氧代-7-氮杂螺[3.5]壬烷-7-甲酸叔丁酯