2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈
Benzonitrile,4-methoxy-5-[3-(4-morpholinyl)propoxy]-2-nitro-
CAS: 675126-26-8
Molecular Formula: C15H19N3O5
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈 - Names and Identifiers
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈 - Physico-chemical Properties
| Molecular Formula | C15H19N3O5 |
| Molar Mass | 321.33 |
| Density | 1.29 |
| Melting Point | 127℃ |
| Boling Point | 522.3±50.0 °C(Predicted) |
| pKa | 6.96±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈 - Reference Information
| biological activity | Gefitinib importance 1 is an impurity of Gefitinib. Gefitinib is a potent, orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 54 nM) and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib can also induce autophagy in cells. Gefitinib has anti-tumor activity. |
| Use | gefitinib intermediate |
Last Update：2024-04-09 02:00:10
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