2-氟-4-三氟甲基硫代苯甲酰胺 - Names and Identifiers
2-氟-4-三氟甲基硫代苯甲酰胺 - Physico-chemical Properties
Molecular Formula | C8H5F4NS
|
Molar Mass | 223.19 |
Density | 1.451±0.06 g/cm3(Predicted) |
Boling Point | 240.6±50.0 °C(Predicted) |
Flash Point | 99.316°C |
Vapor Presure | 0.038mmHg at 25°C |
pKa | 11.81±0.29(Predicted) |
Refractive Index | 1.529 |
2-氟-4-三氟甲基硫代苯甲酰胺 - Introduction
Nature:
-Appearance: 2-Fluoro-4-(trifluoromethyl)thiobenzamide exists in a white to light yellow crystalline form.
-Solubility: It can be dissolved in some organic solvents (such as dichloromethane and ether), but its solubility in water is low.
-Melting point: Its melting point is 119-121 degrees Celsius.
-Chemical properties: It is an organic sulfur compound, containing fluorine and trifluoromethyl groups, with strong electron attractive and active.
Use:
- 2-Fluoro-4-(trifluoromethyl)thiobenzamide has certain application value in organic synthesis, and can be used as reagent, intermediate or catalyst.
-It can be used to synthesize other compounds, such as drugs, pesticides, dyes and synthetic materials.
Method:
The synthetic method of 2-Fluoro-4-(trifluoromethyl)thiobenzamide is as follows:
First, under appropriate reaction conditions, 2-fluoronitrobenzene and trifluoromethyl thiourea are reacted to generate 2-fluoro-4-nitromethylbenzamide. Subsequently, the nitro group is reduced to an amino group by a hydrogenation reduction reaction or a Cyclization-dehydration reaction under basic conditions and dehydrated to give the target product 2-Fluoro-4-(trifluoromethyl)thiobenzamide.
Safety Information:
- 2-Fluoro-4-(trifluoromethyl)thiobenzamide has low toxicity under normal use conditions. However, as a chemical substance, any individual who comes into contact with it should pay attention to safe handling and follow relevant laboratory safety regulations.
-During handling and storage, avoid prolonged exposure to the air and avoid mixing flammable substances. Keep away from ignition and high temperature.
-Wear appropriate protective gloves, glasses and protective clothing when using. After use, pay attention to wash the skin and avoid inhaling its dust or gas. If you feel unwell, you should seek medical attention in time.
Last Update:2024-04-09 21:01:54