2-叔丁氧基羰氨甲基-苯甲酸
Boc-N-Me-Abz-OH
CAS: 141871-02-5
Molecular Formula: C13H17NO4
2-叔丁氧基羰氨甲基-苯甲酸 - Names and Identifiers
| Name | Boc-N-Me-Abz-OH |
| Synonyms | Boc-MANT BOC-MEABZ-OH BOC-N-ME-ABZ-OH Boc-N-Me-Abz-OH BOC-N-ME-2-ABZ-OH BOC-N-ME-AMINOBENZOIC ACID ANTHRANILIC ACID, N-BOC-N-METHYL BOC-N-METHYL-2-AMINOBENZOIC ACID N-T-BUTOXYCARBONYL-N-METHYL-2-AMINOBENZOIC ACID 2-(tert-Butoxycarbonyl-methyl-amino)-benzoic acid 2-[(tert-butoxycarbonyl)(methyl)amino]benzoic acid |
| CAS | 141871-02-5 |
| InChI | InChI=1/C13H17NO4/c1-13(2,3)18-12(17)14(4)10-8-6-5-7-9(10)11(15)16/h5-8H,1-4H3,(H,15,16) |
2-叔丁氧基羰氨甲基-苯甲酸 - Physico-chemical Properties
| Molecular Formula | C13H17NO4 |
| Molar Mass | 251.28 |
| Density | 1.199±0.06 g/cm3(Predicted) |
| Boling Point | 367.0±25.0 °C(Predicted) |
| Flash Point | 175.8°C |
| Vapor Presure | 4.94E-06mmHg at 25°C |
| Appearance | Yellow powder |
| pKa | 3.68±0.36(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.56 |
| MDL | MFCD00237567 |
2-叔丁氧基羰氨甲基-苯甲酸 - Introduction
2-tert-butoxycarbonylaminomethyl-benzoic acid, chemical formula C14H19NO4, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 2-tert-butoxycarbonylaminomethyl-benzoic acid is commonly white to yellowish crystalline powder.
2. Solubility: It is soluble in most organic solvents, such as methanol, ethanol, dichloromethane, etc.
3. Melting point: about 60-70°C.
4. Stability: relatively stable at room temperature.
Use:
1. pharmaceutical field: 2-tert-butoxycarbonylaminomethyl-benzoic acid is a drug intermediate, commonly used in the synthesis of biologically active molecules. It is widely used in the synthesis of anti-inflammatory, antibacterial, anti-tumor drugs.
2. Other fields: 2-tert-butoxycarbonylaminomethyl-benzoic acid can also be used in the production of functional coatings, dyes and other chemical products.
Preparation Method:
The preparation of 2-tert-butoxycarbonylaminomethyl-benzoic acid can be carried out by the following steps:
1. benzoyl chloride is reacted with methanol to obtain benzoyl methyl ether.
2. reacting benzoyl methyl ether with tert-butylamine to obtain N-tert-butoxybenzamide.
3. Finally, N-tert-butoxybenzamide is subjected to hydrazide to generate 2-tert-butoxycarbonylaminomethyl-benzoic acid.
Safety Information:
1. 2-tert-butoxycarbonylaminomethyl-benzoic acid may have irritating effect on eyes, skin and mucous membrane, and should be washed with plenty of water in time after contact.
2. use should wear appropriate protective equipment, such as protective glasses, gloves and protective clothing.
3. Avoid inhaling dust or steam and ensure that the operating site is well ventilated.
4. in the use and storage process, please follow the relevant safety procedures and protective measures.
5. such as eating or other accidents, please timely medical treatment and bring packaging for processing.
Nature:
1. Appearance: 2-tert-butoxycarbonylaminomethyl-benzoic acid is commonly white to yellowish crystalline powder.
2. Solubility: It is soluble in most organic solvents, such as methanol, ethanol, dichloromethane, etc.
3. Melting point: about 60-70°C.
4. Stability: relatively stable at room temperature.
Use:
1. pharmaceutical field: 2-tert-butoxycarbonylaminomethyl-benzoic acid is a drug intermediate, commonly used in the synthesis of biologically active molecules. It is widely used in the synthesis of anti-inflammatory, antibacterial, anti-tumor drugs.
2. Other fields: 2-tert-butoxycarbonylaminomethyl-benzoic acid can also be used in the production of functional coatings, dyes and other chemical products.
Preparation Method:
The preparation of 2-tert-butoxycarbonylaminomethyl-benzoic acid can be carried out by the following steps:
1. benzoyl chloride is reacted with methanol to obtain benzoyl methyl ether.
2. reacting benzoyl methyl ether with tert-butylamine to obtain N-tert-butoxybenzamide.
3. Finally, N-tert-butoxybenzamide is subjected to hydrazide to generate 2-tert-butoxycarbonylaminomethyl-benzoic acid.
Safety Information:
1. 2-tert-butoxycarbonylaminomethyl-benzoic acid may have irritating effect on eyes, skin and mucous membrane, and should be washed with plenty of water in time after contact.
2. use should wear appropriate protective equipment, such as protective glasses, gloves and protective clothing.
3. Avoid inhaling dust or steam and ensure that the operating site is well ventilated.
4. in the use and storage process, please follow the relevant safety procedures and protective measures.
5. such as eating or other accidents, please timely medical treatment and bring packaging for processing.
Last Update：2024-04-09 21:00:56
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Product Name: 2-(N-Boc-N-methylamino)benzoic acid Visit Supplier Webpage Request for quotationCAS: 141871-02-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
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Spot supply
Product Name: 2-[[(1,1-Dimethylethoxy)carbonyl]methylamino]benzoic acid Visit Supplier Webpage Request for quotationCAS: 141871-02-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-[[(1,1-Dimethylethoxy)carbonyl]methylamino]benzoic acid Visit Supplier Webpage Request for quotation
CAS: 141871-02-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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CAS: 141871-02-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
2-叔丁氧基羰氨甲基-苯甲酸
3-硝基邻苯二甲酰胺(二酰胺)
氧氟沙星杂质6 醋酸盐 (氧氟沙星EP杂质F 醋酸盐)
3-三甲基硅基-2-恶唑烷酮
2-(哌啶-4-基硫基)吡啶二盐酸盐
11-[(叔丁氧羰基)氨基]十一烷酸
FMOC-MEASP(OBN)-OH FMOC-N-ME-ASP(OBZL)-OHFMOC-N-甲基L-天冬氨酸4-苄酯
Adenosine Impurity 9
3-硝基邻苯二甲酰胺(二酰胺)
氧氟沙星杂质6 醋酸盐 (氧氟沙星EP杂质F 醋酸盐)
3-三甲基硅基-2-恶唑烷酮
2-(哌啶-4-基硫基)吡啶二盐酸盐
11-[(叔丁氧羰基)氨基]十一烷酸
FMOC-MEASP(OBN)-OH FMOC-N-ME-ASP(OBZL)-OHFMOC-N-甲基L-天冬氨酸4-苄酯
Adenosine Impurity 9