2-((tert-butoxycarbonyl) amino)-2-ethylbutyric acid (Boc-Deg-OH) is an organic compound. Its chemical formula is C13H25NO5, and the compound contains a tert-butoxycarbonyl protecting group and an amino group and an ethyl butyric acid group.
Boc-Deg-OH have the following properties:
-Appearance: White to yellow solid
-melting point: about 40-45 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide, chloroform and methanol
Boc-Deg-OH has a wide range of applications:
-Protecting group in chemical synthesis: Because the Boc group has a good protective effect on the amino group, Boc-Deg-OH is often used in organic synthesis as a reagent for protecting the amino group.
-Drug synthesis: Boc-Deg-OH is one of the commonly used reagents in drug synthesis, which can be used to synthesize various compounds containing amino groups, such as peptides, polypeptides and drugs.
The following is a common method of preparing Boc-Deg-OH:
1. tert-Butyl chloroformic acid (tert-butyl chloroformate) was prepared by dissolving tert-butyl alcohol (tert-butanol) in dry dimethyl sulfoxide (DMSO).
2. tert-Butyl chloroformic acid was added to ethylbutoxylamine (diethylaminoethanol) to form the product Boc-Deg-OH.
3. Finally, the product is purified by solvent volatilization and crystallization.
Safety information about Boc-Deg-OH:
-Avoid inhalation, ingestion and contact with skin.
-Wear appropriate protective gloves, goggles and protective clothing when handling.
-Operate in a well-ventilated place to avoid dust and vapor.
-If accidentally touched or taken by mistake, please seek medical attention.