2-methyl-2-(3-(trifluoromethoxy)phenyl)propan-1-ol - Names and Identifiers
2-methyl-2-(3-(trifluoromethoxy)phenyl)propan-1-ol - Introduction
2-methyl-2-(3-(trifluoromethoxy)phenyl)propan-1-ol is an organic compound with the chemical formula C12H15F3O2. It is a colorless liquid with a benzene fragrance. The following is a basic description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Molecular weight: 248.24g/mol
-Melting Point: No Data
-Boiling point: 315-316 ° C
-Density: 1.18 g/mL
-Refractive Index: 1.504
-Solubility: Soluble in common organic solvents such as ethanol and dimethylformamide
Use:
- 2-methyl-2-(3-(trifluoromethoxy)phenyl)propan-1-ol is an organic reagent commonly used in chemical synthesis reactions.
-It can be used as a chemical intermediate for carbonyl reduction reactions in organic synthesis, oxidation reactions of aromatic compounds, etc.
-The compound can also be used in research and preparation in the field of medicine.
Method:
The synthesis method of 2-methyl-2-(3-(trifluoromethoxy)phenyl)propan-1-ol is relatively complicated, and multi-step or organic synthesis methods are generally used, here is one possible synthetic route:
1. Trifluoromethyl ether was synthesized from trifluoroformaldehyde.
2. Trifluoromethyl ether is reacted with P-methylphenol in the presence of a base to obtain p-methyl-3-trifluoromethoxybenzene.
3. The addition reaction of p-methyl -3-trifluoromethoxybenzene and Quaternary pentanedione produces 2-methyl -2-(3-(trifluoromethoxy) phenyl) acetone.
4. Finally, 2-methyl-2-(3-(trifluoromethoxy)phenyl) acetone was reduced to obtain the target product 2-methyl-2-(3-(trifluoromethoxy)phenyl)propan-1-ol.
Safety Information:
-Specific toxicity information for this compound can be obtained by referring to the relevant Safety Data Sheet (SDS) or contacting the chemical supplier.
-During the operation, appropriate protective measures must be taken, such as wearing chemical protective glasses, gloves and laboratory coats.
-Avoid contact with skin, eyes and mucous membranes. In case of contact, rinse immediately with plenty of water and seek medical attention.
-Please store and handle the compound properly to avoid accidents caused by mixing with other chemicals or improper use. Please follow the relevant regulations and operating procedures.
Last Update:2024-04-09 21:00:56