2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole - Names and Identifiers
Name | 2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole
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Synonyms | 2-Chloro-5-trifluoromethyl-1,3,4-thiadiazole 2-Chloro-5-trifluoromethyl-[1,3,4]-thiadiazole 2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole 5-Chloro-2-(trifluoromethyl)-1,3,4-thiadiazole 1,3,4-Thiadiazole, 2-chloro-5-(trifluoromethyl)-
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CAS | 53645-98-0
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2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole - Physico-chemical Properties
Molecular Formula | C3ClF3N2S
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Molar Mass | 188.56 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole - Risk and Safety
2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole - Introduction
2-chroo-5-(trifluoromethyl)-1,3,4-thiadiazole (2-chroo-5-(trifluoromethyl)-1,3,4-thiadiazole) is an organic compound with the following properties:
Physical Properties:
-Molecular formula: C2ClF3N2S
-Molecular weight: 174.55g/mol
-Appearance: Colorless to light yellow solid
-Melting point: 88-92 degrees Celsius
-Boiling point: 211-214 degrees Celsius
-Relative density: 1.76
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide, insoluble in water
Chemical Properties:
2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole is an organic diazo derivative containing a thiadiazo group. It can occur a series of reactions, such as the reaction of the reaction, condensation reaction and electrophilic substitution reaction, with high reactivity.
Use:
2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole is mainly used in the field of organic synthesis and can be used as an intermediate for pesticides, medicines and dyes. It is also used as a synthetic raw material for anti-tumor, antibacterial, antiviral, anti-inflammatory and other compounds in drug research.
Preparation Method:
2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole can be prepared by a variety of synthetic methods, one of which is a common method of malonyl diarylamine and suspended sodium nitroso Reaction, and then proceed to oxidation, substitution and deacylation steps.
Safety Information:
Because 2-choro-5-(trifluoromethyl)-1,3,4-thiadiazole has high reactivity, it is necessary to pay attention to safety during use. It may cause irritation and damage to the skin, eyes and respiratory tract, so appropriate protective measures such as wearing protective glasses, gloves and masks are required. At the same time, it should be avoided from direct contact with fire sources and high temperature conditions to avoid explosion or fire. It should be sealed and stored in a dark, dry and well-ventilated place. Observe relevant environmental and safety regulations when handling and disposing of waste.
Last Update:2024-04-09 21:11:58