2-bromo-6-(hydroxymethyl)-3-pyridinol

2-bromo-6-(hydroxymethyl)-3-pyridinol - Names and Identifiers

Name	2-Bromo-6-(hydroxymethyl)-3-pyridinol
Synonyms	2-Bromo-6-(hydroxymethyl)-3-pyridinol 2-bromo-6-(hydroxymethyl)-3-pyridinol 2-Pyridinemethanol, 6-bromo-5-hydroxy- 2-bromo-6-(hydroxymethyl)pyridin-3-ol(WX191869)
CAS	168015-04-1

2-bromo-6-(hydroxymethyl)-3-pyridinol - Physico-chemical Properties

Molecular Formula	C6H6BrNO2
Molar Mass	204.02134
Density	1.836±0.06 g/cm3(Predicted)
Melting Point	127-128°
Boling Point	424.0±40.0 °C(Predicted)
pKa	4.24±0.10(Predicted)
Storage Condition	Room Temprature
Sensitive	Irritant
MDL	MFCD09702158

2-bromo-6-(hydroxymethyl)-3-pyridinol - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Hazard Class	IRRITANT

2-bromo-6-(hydroxymethyl)-3-pyridinol - Introduction

2-Bromo-6-(hydroxymethyl)-3-pyridinol is an organic compound with the chemical formula C7H7BrNO2. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2-Bromo-6-(hydroxymethyl)-3-pyridinol is a white to off-white crystalline solid.
-Solubility: It is slightly soluble in water, soluble in ethanol, ether, chloroform and other organic solvents.

Use:
-Pharmaceutical field: 2-Bromo-6-(hydroxymethyl)-3-pyridinol can be used as a drug intermediate, such as the synthesis of drugs containing pyridine structure.
-Pesticide field: It can also be used to synthesize some pesticide raw materials.

Preparation Method:
2-Bromo-6-(hydroxymethyl)-3-pyridinol synthesis method has a variety of ways, the following is one of the commonly used preparation method:
1. First, 2-amino -6-hydroxymethyl pyridine is reacted with bromoacetic acid to generate 2-hydroxymethyl -6-(hydroxymethyl) pyridine under the catalysis of base.
2. Then, 2-hydroxymethyl -6-(hydroxymethyl) pyridine reacts with hydrochloric acid to generate 2-Bromo-6-(hydroxymethyl)-3-pyridinol under the catalysis of alkali.

Safety Information:
- 2-Bromo-6-(hydroxymethyl)-3-pyridinol has low toxicity, but it is still necessary to pay attention to safe use.
-Wear appropriate protective equipment such as lab gloves, glasses, and lab coats during operation.
-Avoid contact with skin, eyes and respiratory tract. In case of contact, flush immediately with plenty of water and seek medical help.
-When storing, keep away from fire and oxidant, and store in a dry, cool, well-ventilated place.

Last Update：2024-04-09 21:01:54