2-amino-6-methyl-5-(prop-2-yn-1-yl)pyrimidin-4(1H)-one - Names and Identifiers
2-amino-6-methyl-5-(prop-2-yn-1-yl)pyrimidin-4(1H)-one - Physico-chemical Properties
Molecular Formula | C8H9N3O
|
Molar Mass | 163.18 |
Density | 1.21g/cm3 |
Boling Point | 295.1°C at 760 mmHg |
Flash Point | 132.3°C |
Vapor Presure | 0.00156mmHg at 25°C |
Refractive Index | 1.589 |
2-amino-6-methyl-5-(prop-2-yn-1-yl)pyrimidin-4(1H)-one - Introduction
4-Methyl-6-hydroxy-5-(2-propynyl)-2-pyrimidinamine is an organic compound with the formula C9H10N4O and a structure containing an amino group (-NH2), a hydroxyl group (-OH), a methyl group (-CH3), and a propargyl group (-C≡CH2). The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-melting point: about 120-124 ℃
-Solubility: Soluble in water and most organic solvents
Use:
- 4-Methyl-6-hydroxy-5-(2-propynyl)-2-pyrimidinamine is an important intermediate compound, often used in the synthesis of biologically active compounds.
-In the field of medicine, it is commonly used in the synthesis of antiviral drugs and anti-tumor drugs.
Preparation Method:
The preparation method of -4-Methyl-6-hydroxy-5-(2-propynyl)-2-pyrimidinamine is complicated, and it usually needs to be synthesized by multi-step reaction.
-A common synthesis method is to start with 2-amino-4-hydroxy-6-methylpyrimidine, after appropriate reaction steps, introduce propargyl functional group to obtain the target product.
Safety Information:
- 4-Methyl-6-hydroxy-5-(2-propynyl)-2-pyrimidinamine is an organic compound, which has certain toxicity and irritation. Please strictly abide by the laboratory operating specifications.
-Wear appropriate personal protective equipment such as lab gloves and goggles during operation.
-Avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water and seek medical help.
-When using and storing, please keep it away from fire sources and flammable substances, and ensure a well-ventilated environment.
Last Update:2024-04-09 15:18:00