Name | 2-KETO-D-GLUCOSE |
Synonyms | Mannosone Nsc120040 D-GLUCOSONE 2-KETO-D-GLUCOSE D-Arabino-hexos-2-ulose (3S,4R,5R)-3,4,5,6-tetrahydroxy-2-oxohexanal |
CAS | 1854-25-7 |
Molecular Formula | C6H10O6 |
Molar Mass | 178.14 |
Melting Point | 118-120°C |
Solubility | Methanol (Slightly), Water (Slightly) |
Appearance | Solid |
Color | Off-White to Dark Yellow |
Storage Condition | Hygroscopic, Store under Inert atmosphere -20°C Freezer |
Stability | Hygroscopic |
In vitro study | Pyrroloquinoline quinone-dependent 2-keto-D-glucose (2KG) dehydrogenase (2KGDH) has high specificity for the oxidation of 2-Keto-D-Glucose to 2-keto-D-gluconic acid (2KGA). P. aureofaciens ( Pa 2KGDH) specifically preferred 2KG as a substrate and oxidized the C-1 position of 2KG, indicating that the enzyme is a 2KGDH. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29144000 |
biological activity | 2-Keto-D-Glucose (D-Glucosone) is a key intermediate in the secondary metabolic pathway leading to the antibiotic corticosterone. 2-Keto-D-Glucose is also an intermediate in the conversion of D-glucose to D-fructose. 2-Keto-D-Glucose is present in a variety of natural sources, including fungi, algae, and shellfish. |