Name | 2-Iodothiophene |
Synonyms | 2-IODTHIOPHENE 2-Iodothophene 2-Iodothyophene 2-Iodothiophene 2-iodo-thiophen 2-THIENYL IODIDE alpha-Iodothiophene |
CAS | 3437-95-4 |
EINECS | 222-342-1 |
InChI | InChI=1/C4H3IS/c5-4-2-1-3-6-4/h1-3H |
InChIKey | ROIMNSWDOJCBFR-UHFFFAOYSA-N |
Molecular Formula | C4H3IS |
Molar Mass | 210.04 |
Density | 1.902 g/mL at 25 °C (lit.) |
Melting Point | -40 °C (lit.) |
Boling Point | 73 °C/15 mmHg (lit.) |
Flash Point | 160°F |
Vapor Presure | 1.14mmHg at 25°C |
Appearance | Liquid |
Specific Gravity | 1.902 |
Color | Clear yellow-green to red-brown |
BRN | 104666 |
Storage Condition | 2-8°C |
Sensitive | Light Sensitive |
Refractive Index | n20/D 1.651(lit.) |
Physical and Chemical Properties | Colorless liquid. Melting Point -40 °c, boiling point 80-81 °c (2.67kPa). |
Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. S27 - Take off immediately all contaminated clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3 |
TSCA | T |
HS Code | 29349990 |
Hazard Class | IRRITANT |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
use | for organic synthesis. |
production method | 35g(0.42mol) of thiophene and 50 ml of benzene are mixed, and 75g(0.35mol) of yellow mercury oxide and 109g(0.43mol) of iodine are alternately added in different times under stirring and cooling. Filter and wash the filter residue with ether. The washing filtrate was combined, washed with dilute sodium thiosulfate solution to remove excess iodine, dried by anhydrous calcium chloride and evaporated to remove ether and benzene, distilled under reduced pressure, and the 73 ℃(2.0kPa) fraction was collected to obtain 63-66g2-iodothiophene. Yield 72-75%. |