2-Hydrazinopyrazine
2-Hydrazinopyrazine
CAS: 54608-52-5
Molecular Formula: C4H6N4
2-Hydrazinopyrazine - Names and Identifiers
2-Hydrazinopyrazine - Physico-chemical Properties
| Molecular Formula | C4H6N4 |
| Molar Mass | 110.12 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Melting Point | 109-113℃ |
| Boling Point | 246.3±23.0 °C(Predicted) |
| Water Solubility | Slightly soluble in water. |
| Appearance | Solid |
| Color | Yellow |
| pKa | 5.10±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| MDL | MFCD04114555 |
2-Hydrazinopyrazine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29339900 |
2-Hydrazinopyrazine - Reference Information
| introduction | pyrazin-2-hydrazine is a yellow or yellow-white solid, slightly soluble in water. Pyrazin-2-hydrazine is a pyrazine derivative, which is not prone to electrophilic substitution reactions, but it is easy to react with nucleophiles and is not stable. It should be stored at low temperature as far as possible. In addition, pyrazin-2-hydrazine It is related to the synthesis of sitagliptin used to improve blood sugar control in patients with type 2 diabetes. |
| Uses | Pyrazin-2-hydrazine can be used as a pharmaceutical intermediate, flavor, and flavor intermediate. In addition, it is also used in the synthesis of livestock insect repellents and dyes. In the synthetic transformation, the terminal amino group can become a diazo compound under the action of sodium nitrite and acid, and then perform subsequent transformations including click reaction with the terminal alkyne. In addition, pyrazin-2-hydrazine can also undergo cyclization condensation reaction with aldehyde groups. |
| synthesis method | synthesis of pyrazine -2-hydrazine: adding 35% hydrazine hydrate (4.48g,48.9 mmol) to the vacuum dried reaction bottle, then adding 2-chloropyrazine (779 mL,8.73 mmol) dropwise into the reaction system, and stirring the reaction mixture at 65°C for 12 hours; after waiting for the reaction system to cool completely, the reaction mixture is extracted with a 10% mixed solution of isopropanol and dichloride (5 × 10 mL) to separate the organic layer. The organic phase is dried with anhydrous sodium sulfate, filtered to remove the sodium sulfate solid, and the obtained combined organic layer is evaporated under reduced pressure to obtain the target product. |
Last Update：2024-04-09 15:16:51
Supplier List
Product Name: 2-Hydrazinopyrazine Request for quotation
CAS: 54608-52-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 54608-52-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 2-Hydrazinopyrazine Request for quotationCAS: 54608-52-5
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 2-Hydrazinopyrazine Request for quotationCAS: 54608-52-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 2-Hydrazinopyrazine Visit Supplier Webpage Request for quotationCAS: 54608-52-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 2-(pyrazin-2-yl)hydrazine Visit Supplier Webpage Request for quotationCAS: 54608-52-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(pyrazin-2-yl)hydrazine Visit Supplier Webpage Request for quotationCAS: 54608-52-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-Hydrazinylpyrazine Visit Supplier Webpage Request for quotation
CAS: 54608-52-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 54608-52-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: 2-Hydrazinopyrazine Request for quotation
CAS: 54608-52-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 54608-52-5
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 2-Hydrazinopyrazine Request for quotationCAS: 54608-52-5
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 2-Hydrazinopyrazine Request for quotationCAS: 54608-52-5
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: 2-Hydrazinopyrazine Visit Supplier Webpage Request for quotationCAS: 54608-52-5
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 2-(pyrazin-2-yl)hydrazine Visit Supplier Webpage Request for quotationCAS: 54608-52-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 2-(pyrazin-2-yl)hydrazine Visit Supplier Webpage Request for quotationCAS: 54608-52-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 2-Hydrazinylpyrazine Visit Supplier Webpage Request for quotation
CAS: 54608-52-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 54608-52-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
2-Hydrazinopyrazine
3-(1,1-dimethylethyl)-7,12-dioxaspiro[5.6]dodecane
琼脂糖凝胶CL-4B
溴代对苯二甲酸二甲酯
1481230-07-2
bis(acetato-o)tetrahydroxytri-lea
2-苯甲氧基苯甲酸
A-HYDROXY-3-PHENOXY BENZACETONITRILE
(1-Hexadecyl)triphenylphosphonium bromide
methyl Protodioscin
3-(1,1-dimethylethyl)-7,12-dioxaspiro[5.6]dodecane
琼脂糖凝胶CL-4B
溴代对苯二甲酸二甲酯
1481230-07-2
bis(acetato-o)tetrahydroxytri-lea
2-苯甲氧基苯甲酸
A-HYDROXY-3-PHENOXY BENZACETONITRILE
(1-Hexadecyl)triphenylphosphonium bromide
methyl Protodioscin